UBC9/YDL064W Protein Information Help

Standard Name Ubc9p
Systematic Name Ydl064wp
ORF Classification Verified
Description SUMO-conjugating enzyme involved in the Smt3p conjugation pathway; nuclear protein required for S- and M-phase cyclin degradation and mitotic control; involved in proteolysis mediated by the anaphase-promoting complex cyclosome (APCC) (1, 2, 3)
Name Description UBiquitin-Conjugating
Experimental Data
Molecules/cell 2600 4
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 157
Molecular Weight (Da) 17,911
Isoelectric Point (pI) 9.98

Click on image for expanded interactive view
pbrowse

Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Ubc9p (InterPro)
Physical Interactions There are 74 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000013796C | P50623
MIPS: YDL064W
NCBI: 110590307 | 110590308 | 110590309 | 110590310 | 1431070 | 149241624 | 149241625 | 1717862 | 317455355 | 317455357 | 6320139 | 634089 | NP_010219.1 | NM_001180123.1
GenBank/EMBL/DDBJ: DAA11793.1 | X82538 | Z74112
External Classifications EC: 6.3.2.- [Acid-Amino-Acid Ligases (Peptide Synthases)]
Amino Acid Sequence (or in FASTA format)
 
       1  MSSLCLQRLQ EERKKWRKDH PFGFYAKPVK KADGSMDLQK WEAGIPGKEG
      51  TNWAGGVYPI TVEYPNEYPS KPPKVKFPAG FYHPNVYPSG TICLSILNED
     101  QDWRPAITLK QIVLGVQDLL DSPNPNSPAQ EPAWRSFSRN KAEYDKKVLL
     151  QAKQYSK*

external links for Ubc9p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Aspergillus (AspGD) BioPIXIE MIPS YeastGFP
Candida (CGD) CYC2008 (complexes) Pfam domains YeastRC Public Image Repository
Candida (CandidaDB) Complexome YeastRC Structure Prediction (Seattle)
YGOB DIP

YOGY GeneMANIA


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Ubc9p
1) Seufert W, et al.  (1995) Role of a ubiquitin-conjugating enzyme in degradation of S- and M-phase cyclins. Nature 373(6509):78-81
2) Johnson ES and Blobel G  (1997) Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p. J Biol Chem 272(43):26799-802
3) Dieckhoff P, et al.  (2004) Smt3/SUMO and Ubc9 are required for efficient APC/C-mediated proteolysis in budding yeast. Mol Microbiol 51(5):1375-87
4) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41