MCH1/YDL054C Protein Information

Standard Name	Mch1p 1
Systematic Name	Ydl054cp
ORF Classification	Verified
Description	Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport (1)
Name Description	MonoCarboxylate transporter Homologue 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	486
Molecular Weight (Da)	53,565
Isoelectric Point (pI)	9.67

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Mch1p (InterPro)
Transmembrane Domains	There are 11 total predicted transmembrane domains (TMHMM)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 17 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00000698DD \| Q07376 MIPS: YDL054C NCBI: 1431051 \| 6320149 \| 74627228 \| NP_010229.1 GenBank/EMBL/DDBJ: DAA11802.1 \| Z74102

Amino Acid Sequence (or in FASTA format)
1 MPLSKVEHYL SYHTRLLLPH VLSLQSSHRV AYIFSLLSAV STGFITLISL 51 YSQPWQKHLN YSSWQINTIA SMTNLGMYLT PPILGMIADS HGPITLSLLA 101 IIGFIPSYSY LAYVFNHPEL SLGGNGDSSF NLSIICFVFI GISTSALYFS 151 ALLTCTKLYP HTKLLSISLP TTCYGISSVV GSQLLRIKWF WSSNASSSSS 201 NSDLNLGRVF QTFALVYVVI GLLAWIATSV VSLLHFNEEQ DNQKRLDDQT 251 DVEQSPLLER SNHVQEKFTQ TMLRIFSDPV TYILAVSILL SLGPLEMFIA 301 NMGSLTNLLV QLDAPTLSTK LLSTYALSST FTRLLTGIVA DFFAKKKISI 351 KWILLTFLSL GVCAQLFLLK MTSSASPWGL VPTGSLVGIV YGGLFTVYPT 401 LVLLVWGERS FGTVYGSLLI APAIGSMIFC MLYAKFYDSR CMSGGGDLRN 451 PSCISAVYKY SSIAFVVSAV LSAVVFWKLK SRKLRI*

Amino Acid Sequence (or in FASTA format)

       1  MPLSKVEHYL SYHTRLLLPH VLSLQSSHRV AYIFSLLSAV STGFITLISL
      51  YSQPWQKHLN YSSWQINTIA SMTNLGMYLT PPILGMIADS HGPITLSLLA
     101  IIGFIPSYSY LAYVFNHPEL SLGGNGDSSF NLSIICFVFI GISTSALYFS
     151  ALLTCTKLYP HTKLLSISLP TTCYGISSVV GSQLLRIKWF WSSNASSSSS
     201  NSDLNLGRVF QTFALVYVVI GLLAWIATSV VSLLHFNEEQ DNQKRLDDQT
     251  DVEQSPLLER SNHVQEKFTQ TMLRIFSDPV TYILAVSILL SLGPLEMFIA
     301  NMGSLTNLLV QLDAPTLSTK LLSTYALSST FTRLLTGIVA DFFAKKKISI
     351  KWILLTFLSL GVCAQLFLLK MTSSASPWGL VPTGSLVGIV YGGLFTVYPT
     401  LVLLVWGERS FGTVYGSLLI APAIGSMIFC MLYAKFYDSR CMSGGGDLRN
     451  PSCISAVYKY SSIAFVVSAV LSAVVFWKLK SRKLRI*

external links for Mch1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Mch1p

1)	Makuc J, et al. (2001) The putative monocarboxylate permeases of the yeast Saccharomyces cerevisiae do not transport monocarboxylic acids across the plasma membrane. Yeast 18(12):1131-43