DBP10/YDL031W Protein Information Help

Standard Name Dbp10p 1
Systematic Name Ydl031wp
ORF Classification Verified
Description Putative ATP-dependent RNA helicase of the DEAD-box protein family, constituent of 66S pre-ribosomal particles; essential protein involved in ribosome biogenesis (1, 2)
Name Description Dead Box Protein 1
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 995
Molecular Weight (Da) 112,946
Isoelectric Point (pI) 9.71

Click on image for expanded interactive view
pbrowse

Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Dbp10p (InterPro)
Physical Interactions There are 94 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0001F7BD3E | Q12389
MIPS: YDL031W
NCBI: 1279685 | 1431010 | 2500535 | 330443505 | 341940422 | NP_010253.2
GenBank/EMBL/DDBJ: DAA11821.2 | Z71781 | Z74079
External Classifications EC: 3.6.1.- [Hydrolases acting on acid anhydrides in phosphorous-containing anhydrides]
Amino Acid Sequence (or in FASTA format)
 
       1  MAGVQKRKRD LEDQDDNGSE EDDIAFDIAN EIALNDSESD ANDSDSEVEA
      51  DYGPNDVQDV IEYSSDEEEG VNNKKKAENK DIKKKKNSKK EIAAFPMLEM
     101  SDDENNASGK TQTGDDEDDV NEYFSTNNLE KTKHKKGSFP SFGLSKIVLN
     151  NIKRKGFRQP TPIQRKTIPL ILQSRDIVGM ARTGSGKTAA FILPMVEKLK
     201  SHSGKIGARA VILSPSRELA MQTFNVFKDF ARGTELRSVL LTGGDSLEEQ
     251  FGMMMTNPDV IIATPGRFLH LKVEMNLDLK SVEYVVFDEA DRLFEMGFQE
     301  QLNELLASLP TTRQTLLFSA TLPNSLVDFV KAGLVNPVLV RLDAETKVSE
     351  NLEMLFLSSK NADREANLLY ILQEIIKIPL ATSEQLQKLQ NSNNEADSDS
     401  DDENDRQKKR RNFKKEKFRK QKMPAANELP SEKATILFVP TRHHVEYISQ
     451  LLRDCGYLIS YIYGTLDQHA RKRQLYNFRA GLTSILVVTD VAARGVDIPM
     501  LANVINYTLP GSSKIFVHRV GRTARAGNKG WAYSIVAENE LPYLLDLELF
     551  LGKKILLTPM YDSLVDVMKK RWIDEGKPEY QFQPPKLSYT KRLVLGSCPR
     601  LDVEGLGDLY KNLMSSNFDL QLAKKTAMKA EKLYYRTRTS ASPESLKRSK
     651  EIISSGWDAQ NAFFGKNEEK EKLDFLAKLQ NRRNKETVFE FTRNPDDEMA
     701  VFMKRRRKQL APIQRKATER RELLEKERMA GLSHSIEDEI LKGDDGETGY
     751  TVSEDALKEF EDADQLLEAQ ENENKKKKKP KSFKDPTFFL SHYAPAGDIQ
     801  DKQLQITNGF ANDAAQAAYD LNSDDKVQVH KQTATVKWDK KRKKYVNTQG
     851  IDNKKYIIGE SGQKIAASFR SGRFDDWSKA RNLKPLKVGS RETSIPSNLL
     901  EDPSQGPAAN GRTVRGKFKH KQMKAPKMPD KHRDNYYSQK KKVEKALQSG
     951  ISVKGYNNAP GLRSELKSTE QIRKDRIIAE KKRAKNARPS KKRKF*

external links for Dbp10p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Candida (CGD) BioPIXIE MIPS YeastGFP
Candida (CandidaDB) CYC2008 (complexes) Pfam domains
YGOB Complexome YeastRC Structure Prediction (Seattle)
YOGY DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Dbp10p
1) Burger F, et al.  (2000) Dbp10p, a putative RNA helicase from Saccharomyces cerevisiae, is required for ribosome biogenesis. Nucleic Acids Res 28(12):2315-23
2) Horsey EW, et al.  (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27