YBL111C Protein Information

Systematic Name	Ybl111cp
ORF Classification	Verified
Description	Helicase-like protein encoded within the telomeric Y' element; relocalizes from mitochondrion to cytoplasm upon DNA replication stress (1, 2)

Experimental Data
Molecules/cell	279 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	667
Molecular Weight (Da)	76,246
Isoelectric Point (pI)	8.69

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ybl111cp (InterPro)
Physical Interactions	There are 5 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00001682AA \| Q3E7Y5 MIPS: YBL111C NCBI: 114154879 \| 6319357 \| NP_009439.1 GenBank/EMBL/DDBJ: DAA07014.1 \| Y08934

Amino Acid Sequence (or in FASTA format)
1 MKVSDRRKFE KANFDEFESA LNNKNDLVHC PSITLFESIP TEVRSFYEDE 51 KSGLIKVVKF RTGAMDRKRS FEKIVVSVMV GKNVQKFLTF VEDEPDFQGG 101 PIPSKYLIPK KINLMVYTLF QVHTLKFNRK DYDTLSLFYL NRGYYNELSF 151 RVLERCYEIA SARPNDSSTM RTFTDFVSGT PIVRSLQKST IRKYGYNLAP 201 YMFLLLHVDE LSIFSAYQAS LPGEKKVDTE RLKRDLCPRK PTEIKYFSQI 251 CNDMMNKKDR LGDVLATAQR IRRRYNKNGS SEPRLKTLDG LTSERWIQWL 301 GLESDYHCSF SSTRNAEDVV AGEAASSDHD QKISRVTRKR PREPKSTNDI 351 LVAGRKLFGS SFEFRDLHQL RLCHEIYMAD TPSVAVQAPP GYGKTELFHL 401 PLIALASKGD VKYVSFLFVP YTVLLANCMI RLGRRGCLNV APVRNFIEEG 451 CDGVTDLYVG IYDDLASTNF TDRIAAWENI VECTFRTNNV KLGYLIVDEF 501 HNFETEVYRQ SQFGGITNLD FDAFEKAIFL SGTAPEAVAD AALQRIGLTG 551 LAKKSMDINE LKRSEDLSRG LSSYPTRMFN LIKEKSEVPL GHVHKIWKKV 601 ESQPEEALKL LLALFEIEPE SKAIVVASTT NEVEELACSW RKYFRVVWIH 651 GKLGCCRKGV SHKGVCH*

Amino Acid Sequence (or in FASTA format)

       1  MKVSDRRKFE KANFDEFESA LNNKNDLVHC PSITLFESIP TEVRSFYEDE
      51  KSGLIKVVKF RTGAMDRKRS FEKIVVSVMV GKNVQKFLTF VEDEPDFQGG
     101  PIPSKYLIPK KINLMVYTLF QVHTLKFNRK DYDTLSLFYL NRGYYNELSF
     151  RVLERCYEIA SARPNDSSTM RTFTDFVSGT PIVRSLQKST IRKYGYNLAP
     201  YMFLLLHVDE LSIFSAYQAS LPGEKKVDTE RLKRDLCPRK PTEIKYFSQI
     251  CNDMMNKKDR LGDVLATAQR IRRRYNKNGS SEPRLKTLDG LTSERWIQWL
     301  GLESDYHCSF SSTRNAEDVV AGEAASSDHD QKISRVTRKR PREPKSTNDI
     351  LVAGRKLFGS SFEFRDLHQL RLCHEIYMAD TPSVAVQAPP GYGKTELFHL
     401  PLIALASKGD VKYVSFLFVP YTVLLANCMI RLGRRGCLNV APVRNFIEEG
     451  CDGVTDLYVG IYDDLASTNF TDRIAAWENI VECTFRTNNV KLGYLIVDEF
     501  HNFETEVYRQ SQFGGITNLD FDAFEKAIFL SGTAPEAVAD AALQRIGLTG
     551  LAKKSMDINE LKRSEDLSRG LSSYPTRMFN LIKEKSEVPL GHVHKIWKKV
     601  ESQPEEALKL LLALFEIEPE SKAIVVASTT NEVEELACSW RKYFRVVWIH
     651  GKLGCCRKGV SHKGVCH*

external links for Ybl111cp

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS	YeastRC Public Image Repository
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	GeneMANIA

References cited on this page View Complete Literature Guide for Ybl111cp

1)	Shiratori A, et al. (1999) Systematic identification, classification, and characterization of the open reading frames which encode novel helicase-related proteins in Saccharomyces cerevisiae by gene disruption and Northern analysis. Yeast 15(3):219-53
2)	Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41