FUN19/YAL034C Protein Information

Standard Name	Fun19p 1
Systematic Name	Yal034cp
ORF Classification	Verified
Description	Non-essential protein of unknown function; expression induced in response to heat stress; FUN19 has a paralog, YOR338W, that arose from the whole genome duplication (2, 3, 4)
Name Description	Function Unknown Now 5

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	413
Molecular Weight (Da)	47,068
Isoelectric Point (pI)	10.71

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Fun19p (InterPro)
Physical Interactions	There are 16 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00001D475D \| P28003 MIPS: YAL034C NCBI: 1326058 \| 1723186 \| 37362610 \| 5242 \| 97537625 \| NP_009368.2 GenBank/EMBL/DDBJ: DAA06954.1 \| U12980 \| X62577

Amino Acid Sequence (or in FASTA format)
1 MGLYSPESEK SQLNMNYIGK DDSQSIFRRL NQNLKASNNN NDSNKNGLNM 51 SDYSNNSPYG RSYDVRINQN SQNNGNGCFS GSIDSLVDEH IIPSPPLSPK 101 LESKISHNGS PRMASSVLVG STPKGAVENV LFVKPVWPNG LSRKRYRYAT 151 YGFLSQYKIF SNLAQPYSKN IINRYNNLAY NARHKYSKYN DDMTPPPLPS 201 SSSRLPSPLA SPNLNRQARY NMRKQALYNN NLGKFESDTE WIPRKRKVYS 251 PQRRTMTTSP HRAKKFSPSA STPHTNIASI EAIHDAPQYI PNVSWKKLPD 301 YSPPLSTLPT DSNKSLKIEW KGSPMDLSTD PLRNELHPAE LVLAQTLRLP 351 CDLYLDSKRR LFLEKVYRLK KGLPFRRTDA QKACRIDVNK ASRLFQAFEK 401 VGWLQDSNFT KYL*

Amino Acid Sequence (or in FASTA format)

       1  MGLYSPESEK SQLNMNYIGK DDSQSIFRRL NQNLKASNNN NDSNKNGLNM
      51  SDYSNNSPYG RSYDVRINQN SQNNGNGCFS GSIDSLVDEH IIPSPPLSPK
     101  LESKISHNGS PRMASSVLVG STPKGAVENV LFVKPVWPNG LSRKRYRYAT
     151  YGFLSQYKIF SNLAQPYSKN IINRYNNLAY NARHKYSKYN DDMTPPPLPS
     201  SSSRLPSPLA SPNLNRQARY NMRKQALYNN NLGKFESDTE WIPRKRKVYS
     251  PQRRTMTTSP HRAKKFSPSA STPHTNIASI EAIHDAPQYI PNVSWKKLPD
     301  YSPPLSTLPT DSNKSLKIEW KGSPMDLSTD PLRNELHPAE LVLAQTLRLP
     351  CDLYLDSKRR LFLEKVYRLK KGLPFRRTDA QKACRIDVNK ASRLFQAFEK
     401  VGWLQDSNFT KYL*

external links for Fun19p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
YGOB	BioPIXIE	MIPS	YeastGFP
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome
	DIP
	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Fun19p

1)	Diehl BE and Pringle JR (1991) Molecular analysis of Saccharomyces cerevisiae chromosome I: identification of additional transcribed regions and demonstration that some encode essential functions. Genetics 127(2):287-98
2)	Harris SD, et al. (1992) Molecular analysis of Saccharomyces cerevisiae chromosome I. On the number of genes and the identification of essential genes using temperature-sensitive-lethal mutations. J Mol Biol 225(1):53-65
3)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4)	Sakaki K, et al. (2003) Response of genes associated with mitochondrial function to mild heat stress in yeast Saccharomyces cerevisiae. J Biochem 134(3):373-84
5)	Coleman KG, et al. (1986) Molecular cloning of chromosome I DNA from Saccharomyces cerevisiae: isolation and characterization of the CDC24 gene and adjacent regions of the chromosome. Mol Cell Biol 6(12):4516-25