YFR039C Protein Information

Systematic Name	Yfr039cp
ORF Classification	Uncharacterized
Description	Putative protein of unknown function; may be involved in response to high salt and changes in carbon source; deletion mutant has decreased spore survival in Drosophila feces; YFR039C has a paralog, SHE10, that arose from the whole genome duplication (1, 2, 3, 4)

Experimental Data
Molecules/cell	3170 6

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	510
Molecular Weight (Da)	59,359
Isoelectric Point (pI)	4.5

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Yfr039cp (InterPro)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 3 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013AEDE \| P43611 MIPS: YFR039C NCBI: 1176016 \| 398364375 \| 836794 \| NP_116697.3 GenBank/EMBL/DDBJ: DAA12482.1 \| D50617

Amino Acid Sequence (or in FASTA format)
1 MKAVFKVTTA LLACVFIARY LVCQQNGLGS FATDLQPICR HTEFSVGSLF 51 DSKLVEGSAV SDYLVGKYSQ SIKPLIERYP NSSLKRIMGY FYRFWYNIFS 101 FLRLNELCCS LHSKLGPLLN HLRIAWYYLK PYTDNVKNVL ENPFNSSTDW 151 MKYGSFSADG TLTKPIFETD SETEDYEDDE NENEDEDEDE DEDDVGIEDE 201 NKEYEFDGVQ DGHGNSQLVT AAILQDLSKI IIGSNSHAEL ETYEAESLKM 251 EYEAWIKAID SKIHSAMALL DSEIQSVFEA EVQNKSIEIT RNLDDLNTTV 301 NEQLVFLDSK IKDINCTSKF DPVQNKIKYF DESGQVELEA YITKSSITSI 351 LKNYKIHLLD FEKSLFHSLD SFLTEMAKLA ESIRLENVEV YEEWGDVMIS 401 QWSQRMAYMD VRGLHLEDQY DPAYIEENHS NWLRFMELKK KVISERNRLV 451 KHDLDMTLIL EWITKLKADF QNTKNNIQDT FLQRMNTADT LFKNRELKEQ 501 LEEEFVRQEH *

Amino Acid Sequence (or in FASTA format)

       1  MKAVFKVTTA LLACVFIARY LVCQQNGLGS FATDLQPICR HTEFSVGSLF
      51  DSKLVEGSAV SDYLVGKYSQ SIKPLIERYP NSSLKRIMGY FYRFWYNIFS
     101  FLRLNELCCS LHSKLGPLLN HLRIAWYYLK PYTDNVKNVL ENPFNSSTDW
     151  MKYGSFSADG TLTKPIFETD SETEDYEDDE NENEDEDEDE DEDDVGIEDE
     201  NKEYEFDGVQ DGHGNSQLVT AAILQDLSKI IIGSNSHAEL ETYEAESLKM
     251  EYEAWIKAID SKIHSAMALL DSEIQSVFEA EVQNKSIEIT RNLDDLNTTV
     301  NEQLVFLDSK IKDINCTSKF DPVQNKIKYF DESGQVELEA YITKSSITSI
     351  LKNYKIHLLD FEKSLFHSLD SFLTEMAKLA ESIRLENVEV YEEWGDVMIS
     401  QWSQRMAYMD VRGLHLEDQY DPAYIEENHS NWLRFMELKK KVISERNRLV
     451  KHDLDMTLIL EWITKLKADF QNTKNNIQDT FLQRMNTADT LFKNRELKEQ
     501  LEEEFVRQEH *

external links for Yfr039cp

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
YGOB	BioPIXIE	MIPS	YeastGFP
YOGY	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Yfr039cp

1)	Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
2)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
3)	Musso G, et al. (2008) The extensive and condition-dependent nature of epistasis among whole-genome duplicates in yeast. Genome Res 18(7):1092-9
4)	Coluccio AE, et al. (2008) The yeast spore wall enables spores to survive passage through the digestive tract of Drosophila. PLoS ONE 3(8):e2873
5)	Neiman A (2013) personal communication
6)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41