IRC5/YFR038W Protein Information Help

Standard Name Irc5p 1
Systematic Name Yfr038wp
ORF Classification Verified
Description Putative ATPase containing the DEAD/H helicase-related sequence motif; null mutant displays increased levels of spontaneous Rad52p foci (1, 2)
Name Description Increased Recombination Centers 1
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 853
Molecular Weight (Da) 96,965
Isoelectric Point (pI) 6.22

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Irc5p (InterPro)
Physical Interactions There are 12 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000034F5C8 | P43610
MIPS: YFR038W
NCBI: 42742173 | 836793 | 84028283 | NP_116696.2
GenBank/EMBL/DDBJ: DAA12481.1 | D50617
External Classifications EC: 3.6.1.- [Hydrolases acting on acid anhydrides in phosphorous-containing anhydrides]
Amino Acid Sequence (or in FASTA format)
 
       1  MSRCSNAALM TVVEDAVGAR VAARTRNMSN GVNYREKEVN DLTADISDSD
      51  SDLDSEDNKH GKGDNDTAPI WLQDDVHSDE DIQLDSEDDS DTEAVQAQVV
     101  DKLAKDTKSE QKSLDDELSE MDTKTVSLKL KKLNEFVRQS QVYSSIIADT
     151  LLHRSNEVAN ANTKDNSNSD DEEHSSKKRK TKKKSITDFF KKQKKNEDTT
     201  TQNGAPDDAA IKQPRLLKNC ILKPYQLEGL NWLITLYENG LNGILADEMG
     251  LGKTVQSIAL LAFIYEMDTK GPFLVTAPLS TLDNWMNEFA KFAPDLPVLK
     301  YYGTNGYKER SAKLKNFFKQ HGGTGIVITS YEIILRDTDL IMSQNWKFLI
     351  VDEGHRLKNI NCRLIKELKK INTSNRLLLT GTPLQNNLAE LWSLLNFIMP
     401  DIFADFEIFN KWFDFDSLNL GSGSNSEALN KLINDELQKN LISNLHTILK
     451  PFLLRRLKKV VLANILPPKR EYIINCPMTS AQEKFYKAGL NGKLKKTMFK
     501  ELIKDFFTLN DEYIGHVSNR SIRDFINYKL SGNETSNTDN KINPTLLQMD
     551  KLYKKNLQME ISNKKLQNMM MQLRQIIDST FLFYFPYLHP EDLTLETLLK
     601  TSGKLQILQK LIPPLISEGH KVLIYSQFVN MLDLIEDWCD LNSFATFRID
     651  GSVNNETRKD QLEKFNSSKD KHNIFLLSTR AAGLGINLVG ADTVVLFDSD
     701  WNPQVDLQAM DRCHRIGQES PVIVYRLCCD NTIEHVILTR AANKRNLERM
     751  VIQMGKFNNL KKLALNEGSF LKANKAGVNV TNKDLVQELS MLLMSDESNI
     801  GFENGGQKEN KATEGQLTDK EVEELTNRSL EAYKANRVVD LPHVKLFETT
     851  SGL*

external links for Irc5p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Aspergillus (AspGD) BioPIXIE MIPS YeastGFP
Candida (CGD) CYC2008 (complexes) Pfam domains
Candida (CandidaDB) Complexome

YGOB DIP

YOGY GeneMANIA

References cited on this page View Complete Literature Guide for Irc5p
1) Alvaro D, et al.  (2007) Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination. PLoS Genet 3(12):e228
2) Shiratori A, et al.  (1999) Systematic identification, classification, and characterization of the open reading frames which encode novel helicase-related proteins in Saccharomyces cerevisiae by gene disruption and Northern analysis. Yeast 15(3):219-53