CDC26/YFR036W Protein Information Help

Standard Name Cdc26p
Systematic Name Yfr036wp
Alias Hit3p , Scd26p
ORF Classification Verified
Description Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition (1)
Name Description Cell Division Cycle 2
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 124
Molecular Weight (Da) 14,081
Isoelectric Point (pI) 4.33

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Cdc26p (InterPro)
Physical Interactions There are 36 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000012722C | P14724
MIPS: YFR036W
NCBI: 14318561 | 244397 | 4424 | 45270836 | 461703 | 836791 | NP_116694.1
GenBank/EMBL/DDBJ: DAA12479.1 | AY558473 | D50617 | S79900 | X17118
Amino Acid Sequence (or in FASTA format)
 
       1  MIRRAPTTLQ LSHDDVTSLI DDLNEQKLKQ QLNIEKTKYF QGKNGGSLHS
      51  NTDFQDTSQN IEDNNNDNDN DIDEDDDMSS YNDKAASVAH TRVLNSLHLS
     101  TDSNTAHETS NANDNHNPFY IREE*

external links for Cdc26p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
YGOB BioPIXIE MIPS YeastRC Public Image Repository
YOGY CYC2008 (complexes) Pfam domains

Complexome


DIP


GeneMANIA


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Cdc26p
1) Zachariae W and Nasmyth K  (1999) Whose end is destruction: cell division and the anaphase-promoting complex. Genes Dev 13(16):2039-58
2) Hartwell LH, et al.  (1970) Genetic control of the cell-division cycle in yeast. I. Detection of mutants. Proc Natl Acad Sci U S A 66(2):352-9