PTR3/YFR029W Protein Information Help

Standard Name Ptr3p 1
Systematic Name Yfr029wp
Alias Ssy3p 2 , Raa2p 3
ORF Classification Verified
Description Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes (4, 5)
Name Description Peptide TRansport 1
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 678
Molecular Weight (Da) 76,285
Isoelectric Point (pI) 7.39

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Ptr3p (InterPro)
Physical Interactions There are 16 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI00001329B6 | P43606
MIPS: YFR029W
NCBI: 1176007 | 14318552 | 836784 | NP_116685.1
GenBank/EMBL/DDBJ: DAA12469.1 | D50617
Amino Acid Sequence (or in FASTA format)
 
       1  MHSHRQKWGR QTDIARVLDD IEHDLYLPQR LSLDGATGTD ESHVQYGIVK
      51  DCSVLTCGCC ISESLFNDLC RETSNKQTAC PICQRENVRL LSAIKPLRDL
     101  ARQIDFFRST TGQGESESDE LPAIVKTSPS SSSLSLTPSR SSSTAGLEAD
     151  NKTLSDPTVK EKSSLLELFH IVASKMHNAN TEVGSDHPLT TGTTRDQEEH
     201  TTKENYSSSL LEPNYDDHAN WKILDNASNT RTVPIDNNFS LMSTDVTIPS
     251  TANYQTNSAH DLDEEKEYFF ANCFPMYRKK FQFNTHPKFL GTKSKLFINQ
     301  SISPDCTKFA LITEHKWEIY SINPKDNSPQ LVSCGKSSGE YGPNFNQLTE
     351  QSSSSLSTTS QASKKKKKNW SQRFCKLSND FLIISGSQNI LNVHDIHQNG
     401  KLIYTYVSRF PIRCIDIDPR SQIIAYGITG KDRHTGAEQA LVVIQQITRN
     451  KVTLEPEFPP PITITLPYRD PINTIQLSHD AKYLTCSTAL ESRFLIISLQ
     501  KINEPRLIMK SVRSIDTSLE SEGITDTKLF PGNPNLMCIT STAFNSSPLV
     551  INTKITQING VRTVAQPSML IRVDEIGCKI HKCEISPRND AIAFLDRNGS
     601  VYIMCAPTMM DNNEKRRTIL VETVANAYRA YESATLRFNP EGNKLYILDR
     651  KGTFFVEDFA YGLPQSREIT KCKQIFHK*

external links for Ptr3p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Candida (CGD) BioPIXIE MIPS
Candida (CandidaDB) CYC2008 (complexes) Pfam domains
YGOB Complexome

YOGY GeneMANIA

References cited on this page View Complete Literature Guide for Ptr3p
1) Island MD, et al.  (1991) Isolation and characterization of S. cerevisiae mutants deficient in amino acid-inducible peptide transport. Curr Genet 20(6):457-63
2) Jorgensen MU, et al.  (1998) Mutations in five loci affecting GAP1-independent uptake of neutral amino acids in yeast. Yeast 14(2):103-14
3) McCusker JH and Haber JE  (1990) Mutations in Saccharomyces cerevisiae which confer resistance to several amino acid analogs. Mol Cell Biol 10(6):2941-9
4) Forsberg H and Ljungdahl PO  (2001) Genetic and biochemical analysis of the yeast plasma membrane Ssy1p-Ptr3p-Ssy5p sensor of extracellular amino acids. Mol Cell Biol 21(3):814-26
5) Forsberg H, et al.  (2001) The role of the yeast plasma membrane SPS nutrient sensor in the metabolic response to extracellular amino acids. Mol Microbiol 42(1):215-28