GNA1/YFL017C Protein Information Help

Standard Name Gna1p
Systematic Name Yfl017cp
Alias Pat1p 1
ORF Classification Verified
Description Evolutionarily conserved glucosamine-6-phosphate acetyltransferase required for multiple cell cycle events including passage through START, DNA synthesis, and mitosis; involved in UDP-N-acetylglucosamine synthesis, forms GlcNAc6P from AcCoA (1, 2, 3)
Name Description GlucosamiNe-6-phosphate Acetyltransferase 2
Experimental Data
Molecules/cell 2550 4
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 159
Molecular Weight (Da) 18,135
Isoelectric Point (pI) 4.97

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Gna1p (InterPro)
Physical Interactions There are 15 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000012B8BB | P43577
MIPS: YFL017C
NCBI: 1175928 | 14277743 | 14277744 | 14277745 | 14277746 | 14277747 | 14277748 | 14277749 | 14277750 | 14277753 | 14277754 | 14277755 | 14277756 | 14277757 | 14277758 | 14318503 | 4115733 | 45271018 | 559937 | 836737 | NP_116637.1 | NM_001179949.1
GenBank/EMBL/DDBJ: DAA12423.1 | AB017626 | AY558564 | D50617 | Z46255
External Classifications EC: 2.3.1.4 [Glucosamine-phosphate N-acetyltransferase]
Amino Acid Sequence (or in FASTA format)
 
       1  MSLPDGFYIR RMEEGDLEQV TETLKVLTTV GTITPESFSK LIKYWNEATV
      51  WNDNEDKKIM QYNPMVIVDK RTETVAATGN IIIERKIIHE LGLCGHIEDI
     101  AVNSKYQGQG LGKLLIDQLV TIGFDYGCYK IILDCDEKNV KFYEKCGFSN
     151  AGVEMQIRK*

external links for Gna1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Aspergillus (AspGD) BioPIXIE MIPS YeastGFP
Candida (CGD) CYC2008 (complexes) Pfam domains YeastRC Public Image Repository
Candida (CandidaDB) Complexome YeastRC Structure Prediction (Seattle)
YGOB DIP

YOGY GeneMANIA

References cited on this page View Complete Literature Guide for Gna1p
1) Lin R, et al.  (1996) PAT1, an evolutionarily conserved acetyltransferase homologue, is required for multiple steps in the cell cycle. Genes Cells 1(10):923-42
2) Mio T, et al.  (1999) Saccharomyces cerevisiae GNA1, an essential gene encoding a novel acetyltransferase involved in UDP-N-acetylglucosamine synthesis. J Biol Chem 274(1):424-9
3) Peneff C, et al.  (2001) The crystal structures of Apo and complexed Saccharomyces cerevisiae GNA1 shed light on the catalytic mechanism of an amino-sugar N-acetyltransferase. J Biol Chem 276(19):16328-34
4) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41