AGX1/YFL030W Protein Information

Standard Name	Agx1p
Systematic Name	Yfl030wp
ORF Classification	Verified
Description	Alanine:glyoxylate aminotransferase (AGT), catalyzes the synthesis of glycine from glyoxylate, which is one of three pathways for glycine biosynthesis in yeast; has similarity to mammalian and plant alanine:glyoxylate aminotransferases (1)
Name Description	Alanine:Glyoxylate aminotrans(X)ferase 1
Gene Product	alanine:glyoxylate aminotransferase 2

Experimental Data
Molecules/cell	339 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	385
Molecular Weight (Da)	41,907
Isoelectric Point (pI)	8.01

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Agx1p (InterPro)
Physical Interactions	There are 4 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013AE1E \| P43567 MIPS: YFL030W NCBI: 1175939 \| 14318489 \| 836724 \| 83754407 \| NP_116623.1 \| NM_001179936.1 GenBank/EMBL/DDBJ: DAA12410.1 \| D50617
External Classifications	EC: 2.6.1.44 [Alanine--glyoxylate transaminase]

Amino Acid Sequence (or in FASTA format)
1 MTKSVDTLLI PGPIILSGAV QKALDVPSLG HTSPEFVSIF QRVLKNTRAV 51 FKSAAASKSQ PFVLAGSGTL GWDIFASNFI LSKAPNKNVL VVSTGTFSDR 101 FADCLRSYGA QVDVVRPLKI GESVPLELIT EKLSQNSYGA VTVTHVDTST 151 AVLSDLKAIS QAIKQTSPET FFVVDAVCSI GCEEFEFDEW GVDFALTASQ 201 KAIGAPAGLS ISLCSSRFMD YALNDSKNGH VHGYFSSLRR WTPIMENYEA 251 GKGAYFATPP VQLINSLDVA LKEILEEGLH KRWDLHREMS DWFKDSLVNG 301 LQLTSVSRYP SNMSAHGLTA VYVADPPDVI AFLKSHGVVI AGGIHKDIGP 351 KYIRIGHMGV TACNKNLPYM KNCFDLIKLA LQRKK*

Amino Acid Sequence (or in FASTA format)

       1  MTKSVDTLLI PGPIILSGAV QKALDVPSLG HTSPEFVSIF QRVLKNTRAV
      51  FKSAAASKSQ PFVLAGSGTL GWDIFASNFI LSKAPNKNVL VVSTGTFSDR
     101  FADCLRSYGA QVDVVRPLKI GESVPLELIT EKLSQNSYGA VTVTHVDTST
     151  AVLSDLKAIS QAIKQTSPET FFVVDAVCSI GCEEFEFDEW GVDFALTASQ
     201  KAIGAPAGLS ISLCSSRFMD YALNDSKNGH VHGYFSSLRR WTPIMENYEA
     251  GKGAYFATPP VQLINSLDVA LKEILEEGLH KRWDLHREMS DWFKDSLVNG
     301  LQLTSVSRYP SNMSAHGLTA VYVADPPDVI AFLKSHGVVI AGGIHKDIGP
     351  KYIRIGHMGV TACNKNLPYM KNCFDLIKLA LQRKK*

external links for Agx1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Agx1p

1)	Schlosser T, et al. (2004) Alanine : glyoxylate aminotransferase of Saccharomyces cerevisiae-encoding gene AGX1 and metabolic significance. Yeast 21(1):63-73
2)	Meyer P, et al. (2005) Crystal structure and confirmation of the alanine:glyoxylate aminotransferase activity of the YFL030w yeast protein. Biochimie 87(12):1041-7
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41