RGD2/YFL047W Protein Information Help

Standard Name Rgd2p 1
Systematic Name Yfl047wp
ORF Classification Verified
Description GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p; relocalizes from bud neck to cytoplasm upon DNA replication stress (1, 2)
Name Description RhoGAP domain 1
Experimental Data
Molecules/cell 1750 3
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 714
Molecular Weight (Da) 82,208
Isoelectric Point (pI) 5.64

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Rgd2p (InterPro)
Physical Interactions There are 17 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000013AE3C | P43556
MIPS: YFL047W
NCBI: 1175952 | 16198342 | 836708 | NP_428268.1 | NM_001179920.1
GenBank/EMBL/DDBJ: BAA09194.1 | DAA12393.1 | D50617
Amino Acid Sequence (or in FASTA format)
       1  MLSFCDYFWS EDLVSGLDVL FDRLYHGCEQ CDLFIQLFAS RMQFEVSHGR
      51  QLFGIEAGMD NLKAVQEDED EGVTVSRALR GILQEMSQEG THHLTIASNI
     101  ESLVLQPFSK WCIEHRERIQ YSEKTLLTNV NNFRKSKKYV GKLEKEYFNK
     151  CRQLEEFKRT HFNEDELANA MKSLKIQNKY EEDVAREKDH RFFNRIAGID
     201  FDYKTMKETL QLLLTKLPKT DYKLPLISYS LSNTNNGGEI TKFLLDHMSL
     251  KDIDQAETFG QDLLNLGFLK YCNGVGNTFV NSKKFQYQWK NTAYMFANVP
     301  MPGSEEPTTG ESLISRFNNW DGSSAKEIIQ SKIGNDQGAA KIQAPHISDN
     351  ERTLFRMMDA LAASDKKYYQ ECFKMDALRC SVEELLIDHL SFMEKCESDR
     401  LNAIKKATLD FCSTLGNKIS SLRLCIDKML TLENDIDPTA DLLQLLVKYK
     451  TGSFKPQAIV YNNYYNPGSF QNFGVDLETR CRLDKKVVPL IISSIFSYMD
     501  KIYPDLPNDK VRTSIWTDSV KLSLTHQLRN LLNKQQFHNE GEIFDILSTS
     551  KLEPSTIASV VKIYLLELPD PLIPNDVSDI LRVLYLDYPP LVETALQNST
     601  SSPENQQDDD NEEGFDTKRI RGLYTTLSSL SKPHIATLDA ITTHFYRLIK
     651  ILKMGENGNE VADEFTVSIS QEFANCIIQS KITDDNEIGF KIFYDLLTHK
     701  KQIFHELKRQ NSKN*                                      

external links for Rgd2p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily LoQate
Ashbya (AGD) BOND GPMdb (Mass Spec.) Organelle DB
Candida (CGD) CYC2008 (complexes) MIPS YPL+
YGOB Complexome Pfam domains YeastGFP
YOGY DIP YeastRC Structure Prediction (Seattle) YeastRC Public Image Repository

GeneMANIA


IMP


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Rgd2p
1) Roumanie O, et al.  (2001) Functional characterization of the Bag7, Lrg1 and Rgd2 RhoGAP proteins from Saccharomyces cerevisiae. FEBS Lett 506(2):149-56
2) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76
3) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41