SWP82/YFL049W Protein Information Help

Standard Name Swp82p 1
Systematic Name Yfl049wp
ORF Classification Verified
Description Member of the SWI/SNF chromatin remodeling complex; has an as yet unidentified role in the complex; has identifiable counterparts in closely related yeast species; abundantly expressed in many growth conditions; paralog of Npl6p; relocates to the cytosol under hypoxic conditions (2, 3, 4)
Name Description SWi/snf-associated Protein 1
Experimental Data
Molecules/cell 3180 5
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 623
Molecular Weight (Da) 70,275
Isoelectric Point (pI) 9.47

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Swp82p (InterPro)
Physical Interactions There are 42 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000052FD4 | P43554
MIPS: YFL049W
NCBI: 1175953 | 14318470 | 836706 | NP_116605.1
GenBank/EMBL/DDBJ: DAA12391.1 | D50617
Amino Acid Sequence (or in FASTA format)
       1  MLGEDEGNTV LEKGNNPSVK QGEVGAVFIV PKILIREHER VILKQILQIL
      51  DQDELVQPPL DKFPYKKLEL PKYIDELKTR DATNTSYKMI QLDAYGEKKV
     101  GSNGELFGGR HYLFNTFTFT AHMGVLLVLL QDVIKVLYQS NATHDEDEFI
     151  VQHDQILVME TSEEQTKFLA KNGVIPEESK GSFKYITARS AFVEFGASVI
     201  AGGQRIVDDY WESLAKKQNL SSHQRVFKLS TNLISKISLL RPSFQNNRIS
     251  NANEISANTN NTCTISTSKF ESQYPIVTEQ PSAEIREAYI ENFAKGEHIS
     301  AIVPGQSISG TLELSAQFRV PRYHSKNSFQ QALQMKAMDI PIGRHEELLA
     351  QYESQAPDGS ASISLPNHIP SVNPSNKPIK RMLSSILDIN VSSSKNKKSE
     401  ENEMIKPMNK GQHKNNTSLN INGWKFESLP LKSAENSGKQ QYYRGLPLYE
     451  KNTLLERLKQ LTPNEIKELE HLHDAVFVNT GLQNVRKVRT KKWKKYWQYK
     501  AGIPIGLKRS QLDEFKNKYL KDVLAQTSVT TNFNEITNTD ETITTKRVPN
     551  PNFLGNCNIK DFKPPYIYSH VNKVPQNVAG DKTAVKLDTE VKNTNANPVV
     601  ATDPVAAKPD NLANFSNEVA MNN*                            

external links for Swp82p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
YGOB BioPIXIE MIPS YeastRC Public Image Repository
YOGY CYC2008 (complexes) Pfam domains

Complexome YeastRC Structure Prediction (Seattle)

DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Swp82p
1) Cairns BR, et al.  (1994) A multisubunit complex containing the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated from yeast. Proc Natl Acad Sci U S A 91(5):1950-4
2) Naitou M, et al.  (1997) Expression profiles of transcripts from 126 open reading frames in the entire chromosome VI of Saccharomyces cerevisiae by systematic northern analyses. Yeast 13(13):1275-90
3) Wilson B, et al.  (2006) The RSC chromatin remodeling complex bears an essential fungal-specific protein module with broad functional roles. Genetics 172(2):795-809
4) Ghosh Dastidar R, et al.  (2012) The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation. Cell Biosci 2(1):30
5) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41