AAD6/YFL056C Protein Information

Standard Name	Aad6p 1
Systematic Name	Yfl056cp
ORF Classification	Verified
Description	Putative aryl-alcohol dehydrogenase; involved in oxidative stress response; similar to P. chrysosporium aryl-alcohol dehydrogenase; expression induced in cells treated with the mycotoxin patulin (1, 2, 3, 4)
Name Description	Aryl-Alcohol Dehydrogenase 1, 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	212
Molecular Weight (Da)	23,918
Isoelectric Point (pI)	7.43

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Aad6p (InterPro)
Physical Interactions	There are 1 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00001250A0 \| P43547 MIPS: YFL056C NCBI: 1175960 \| 14318463 \| 51013773 \| 836699 \| NP_116599.1 GenBank/EMBL/DDBJ: DAA12384.1 \| AY693161 \| D50617
External Classifications	EC: 1.1.1.- [Oxidoreductases With NAD+ or NADP+ as acceptor]

Amino Acid Sequence (or in FASTA format)
1 MADLFAPAPE PSTELGRLRV LSKSAGIRVS PLILGGMSIG DAWSEILGSM 51 SKERAFELLD AFYEAGGNFI DTANNYQNEQ SEAWIGEWMV SRKLRDQIVI 101 ATKFTTDYKK YDVGGGKSAN YCGNHKRSLH VSVRDSLRKL QTDWIDILYV 151 HWWDYMSSIE EVMDSLHILV QQARSSIWVC LIRLPGLFLR QITTLNLMVK 201 PLLASIKVNG TC*

Amino Acid Sequence (or in FASTA format)

       1  MADLFAPAPE PSTELGRLRV LSKSAGIRVS PLILGGMSIG DAWSEILGSM
      51  SKERAFELLD AFYEAGGNFI DTANNYQNEQ SEAWIGEWMV SRKLRDQIVI
     101  ATKFTTDYKK YDVGGGKSAN YCGNHKRSLH VSVRDSLRKL QTDWIDILYV
     151  HWWDYMSSIE EVMDSLHILV QQARSSIWVC LIRLPGLFLR QITTLNLMVK
     201  PLLASIKVNG TC*

external links for Aad6p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Aad6p

1)	Delneri D, et al. (1999) Analysis of the seven-member AAD gene set demonstrates that genetic redundancy in yeast may be more apparent than real. Genetics 153(4):1591-600
2)	Delneri D, et al. (1999) Disruption of seven hypothetical aryl alcohol dehydrogenase genes from Saccharomyces cerevisiae and construction of a multiple knock-out strain. Yeast 15(15):1681-9
3)	Dickinson JR, et al. (2003) The catabolism of amino acids to long chain and complex alcohols in Saccharomyces cerevisiae. J Biol Chem 278(10):8028-34
4)	Iwahashi Y, et al. (2006) Mechanisms of patulin toxicity under conditions that inhibit yeast growth. J Agric Food Chem 54(5):1936-42