CCP1/YKR066C Protein Information

Standard Name	Ccp1p
Systematic Name	Ykr066cp
ORF Classification	Verified
Description	Mitochondrial cytochrome-c peroxidase; degrades reactive oxygen species in mitochondria, involved in the response to oxidative stress (1, 2)
Name Description	Cytochrome c Peroxidase

Experimental Data
Molecules/cell	6730 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	361
Molecular Weight (Da)	40,353
Isoelectric Point (pI)	6.33

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ccp1p (InterPro)
Transmembrane Domains	There are 1 total predicted transmembrane domains (TMHMM)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 21 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00001272FE \| P00431 MIPS: YKR066C NCBI: 119389557 \| 13399444 \| 13399445 \| 13399446 \| 13399447 \| 13399448 \| 14719580 \| 157829652 \| 157829653 \| 157829763 \| 157829791 \| 157829794 \| 157829825 \| 157829827 \| 157829828 \| 157829829 \| 157829830 \| 157829831 \| 157829832 \| 157829833 \| 157829835 \| 157829836 \| 157829837 \| 157829839 \| 157829840 \| 157829841 \| 157829842 \| 157829843 \| 157830256 \| 157830257 \| 157830258 \| 157830260 \| 157830261 \| 157830262 \| 157830341 \| 157830542 \| 157830543 \| 157830544 \| 157830546 \| 157830548 \| 157830550 \| 157830551 \| 157830552 \| 157830553 \| 157830556 \| 157830640 \| 157830641 \| 157830644 \| 157830645 \| 157830672 \| 157830673 \| 157830674 \| 157830675 \| 157830768 \| 157830802 \| 157833767 \| 157834737 \| 157834741 \| 157834782 \| 157836776 \| 157836777 \| 157836925 \| 157836926 \| 157837019 \| 157837086 \| 157837134 \| 15826049 \| 158428721 \| 158428733 \| 161761099 \| 161761100 \| 170292376 \| 170292377 \| 170292378 \| 170292379 \| 170292380 \| 170292381 \| 170292382 \| 171177 \| 171352 \| 171848899 \| 171848900 \| 171848901 \| 18655737 \| 194368470 \| 20150376 \| 20151104 \| 20151105 \| 209870482 \| 209870483 \| 220702464 \| 24158790 \| 295982449 \| 295982450 \| 295982451 \| 295982452 \| 295982453 \| 295982454 \| 295982455 \| 295982456 \| 295982457 \| 295982458 \| 295982459 \| 295982460 \| 295982461 \| 295982462 \| 295982463 \| 300508386 \| 300508390 \| 300508392 \| 30749480 \| 30749481 \| 30749482 \| 30749485 \| 311771877 \| 311771878 \| 327200521 \| 3472 \| 350610351 \| 383280141 \| 383280142 \| 409107022 \| 409107023 \| 411024197 \| 411024198 \| 443415 \| 443417 \| 443418 \| 443420 \| 45269733 \| 48425574 \| 48425576 \| 486535 \| 51247422 \| 51247442 \| 543969 \| 55670194 \| 55670196 \| 55670198 \| 55670200 \| 6322919 \| 66361433 \| 66361436 \| 6729914 \| 6730367 \| 6730384 \| 71041533 \| 71041541 \| 71042164 \| 73535271 \| 82407964 \| 82407966 \| 82407968 \| 82407970 \| 82407972 \| 82407974 \| 90108833 \| 90108835 \| 99031834 \| 99031835 \| 99031836 \| 99031837 \| 99031838 \| 99031839 \| 99031840 \| 99032109 \| 99032110 \| 99032111 \| 99032112 \| 99032113 \| 99032114 \| 99032115 \| 99032116 \| NP_012992.1 GenBank/EMBL/DDBJ: DAA09217.1 \| AY557921 \| J01321 \| J01468 \| X62422 \| Z28291
External Classifications	EC: 1.11.1.5 [Cytochrome-c peroxidase]

Amino Acid Sequence (or in FASTA format)
1 MTTAVRLLPS LGRTAHKRSL YLFSAAAAAA AAATFAYSQS QKRSSSSPGG 51 GSNHGWNNWG KAAALASTTP LVHVASVEKG RSYEDFQKVY NAIALKLRED 101 DEYDNYIGYG PVLVRLAWHT SGTWDKHDNT GGSYGGTYRF KKEFNDPSNA 151 GLQNGFKFLE PIHKEFPWIS SGDLFSLGGV TAVQEMQGPK IPWRCGRVDT 201 PEDTTPDNGR LPDADKDADY VRTFFQRLNM NDREVVALMG AHALGKTHLK 251 NSGYEGPWGA ANNVFTNEFY LNLLNEDWKL EKNDANNEQW DSKSGYMMLP 301 TDYSLIQDPK YLSIVKEYAN DQDKFFKDFS KAFEKLLENG ITFPKDAPSP 351 FIFKTLEEQG L*

Amino Acid Sequence (or in FASTA format)

       1  MTTAVRLLPS LGRTAHKRSL YLFSAAAAAA AAATFAYSQS QKRSSSSPGG
      51  GSNHGWNNWG KAAALASTTP LVHVASVEKG RSYEDFQKVY NAIALKLRED
     101  DEYDNYIGYG PVLVRLAWHT SGTWDKHDNT GGSYGGTYRF KKEFNDPSNA
     151  GLQNGFKFLE PIHKEFPWIS SGDLFSLGGV TAVQEMQGPK IPWRCGRVDT
     201  PEDTTPDNGR LPDADKDADY VRTFFQRLNM NDREVVALMG AHALGKTHLK
     251  NSGYEGPWGA ANNVFTNEFY LNLLNEDWKL EKNDANNEQW DSKSGYMMLP
     301  TDYSLIQDPK YLSIVKEYAN DQDKFFKDFS KAFEKLLENG ITFPKDAPSP
     351  FIFKTLEEQG L*

external links for Ccp1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Ccp1p

1)	Charizanis C, et al. (1999) The mitochondrial cytochrome c peroxidase Ccp1 of Saccharomyces cerevisiae is involved in conveying an oxidative stress signal to the transcription factor Pos9 (Skn7). Mol Gen Genet 262(3):437-47
2)	Ho PS, et al. (1984) Kinetics and energetics of intramolecular electron transfer in yeast cytochrome c peroxidase. Biochemistry 23(18):4122-8
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41