CCP1/YKR066C Protein Information Help

Standard Name Ccp1p
Systematic Name Ykr066cp
ORF Classification Verified
Description Mitochondrial cytochrome-c peroxidase; degrades reactive oxygen species in mitochondria, involved in the response to oxidative stress (1, 2)
Name Description Cytochrome c Peroxidase
Experimental Data
Molecules/cell 6730 3
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 361
Molecular Weight (Da) 40,353
Isoelectric Point (pI) 6.33

Click on image for expanded interactive view
pbrowse

Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Ccp1p (InterPro)
Transmembrane Domains There are 1 total predicted transmembrane domains (TMHMM)
Signal Peptide(s) There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions There are 21 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI00001272FE | P00431
MIPS: YKR066C
NCBI: 119389557 | 13399444 | 13399445 | 13399446 | 13399447 | 13399448 | 14719580 | 157829652 | 157829653 | 157829763 | 157829791 | 157829794 | 157829825 | 157829827 | 157829828 | 157829829 | 157829830 | 157829831 | 157829832 | 157829833 | 157829835 | 157829836 | 157829837 | 157829839 | 157829840 | 157829841 | 157829842 | 157829843 | 157830256 | 157830257 | 157830258 | 157830260 | 157830261 | 157830262 | 157830341 | 157830542 | 157830543 | 157830544 | 157830546 | 157830548 | 157830550 | 157830551 | 157830552 | 157830553 | 157830556 | 157830640 | 157830641 | 157830644 | 157830645 | 157830672 | 157830673 | 157830674 | 157830675 | 157830768 | 157830802 | 157833767 | 157834737 | 157834741 | 157834782 | 157836776 | 157836777 | 157836925 | 157836926 | 157837019 | 157837086 | 157837134 | 15826049 | 158428721 | 158428733 | 161761099 | 161761100 | 170292376 | 170292377 | 170292378 | 170292379 | 170292380 | 170292381 | 170292382 | 171177 | 171352 | 171848899 | 171848900 | 171848901 | 18655737 | 194368470 | 20150376 | 20151104 | 20151105 | 209870482 | 209870483 | 220702464 | 24158790 | 295982449 | 295982450 | 295982451 | 295982452 | 295982453 | 295982454 | 295982455 | 295982456 | 295982457 | 295982458 | 295982459 | 295982460 | 295982461 | 295982462 | 295982463 | 300508386 | 300508390 | 300508392 | 30749480 | 30749481 | 30749482 | 30749485 | 311771877 | 311771878 | 327200521 | 3472 | 350610351 | 383280141 | 383280142 | 409107022 | 409107023 | 411024197 | 411024198 | 443415 | 443417 | 443418 | 443420 | 45269733 | 478247501 | 478247502 | 48425574 | 48425576 | 486535 | 51247422 | 51247442 | 543969 | 55670194 | 55670196 | 55670198 | 55670200 | 6322919 | 66361433 | 66361436 | 6729914 | 6730367 | 6730384 | 71041533 | 71041541 | 71042164 | 73535271 | 82407964 | 82407966 | 82407968 | 82407970 | 82407972 | 82407974 | 90108833 | 90108835 | 99031834 | 99031835 | 99031836 | 99031837 | 99031838 | 99031839 | 99031840 | 99032109 | 99032110 | 99032111 | 99032112 | 99032113 | 99032114 | 99032115 | 99032116 | NP_012992.1 | NM_001179856.1
GenBank/EMBL/DDBJ: AAA88709.1 | AAA88710.1 | AAS56247.1 | CAA44288.1 | CAA82145.1 | DAA09217.1 | AY557921 | J01321 | J01468 | X62422 | Z28291
External Classifications EC: 1.11.1.5 [Cytochrome-c peroxidase]
Amino Acid Sequence (or in FASTA format)
       1  MTTAVRLLPS LGRTAHKRSL YLFSAAAAAA AAATFAYSQS QKRSSSSPGG
      51  GSNHGWNNWG KAAALASTTP LVHVASVEKG RSYEDFQKVY NAIALKLRED
     101  DEYDNYIGYG PVLVRLAWHT SGTWDKHDNT GGSYGGTYRF KKEFNDPSNA
     151  GLQNGFKFLE PIHKEFPWIS SGDLFSLGGV TAVQEMQGPK IPWRCGRVDT
     201  PEDTTPDNGR LPDADKDADY VRTFFQRLNM NDREVVALMG AHALGKTHLK
     251  NSGYEGPWGA ANNVFTNEFY LNLLNEDWKL EKNDANNEQW DSKSGYMMLP
     301  TDYSLIQDPK YLSIVKEYAN DQDKFFKDFS KAFEKLLENG ITFPKDAPSP
     351  FIFKTLEEQG L*                                         

external links for Ccp1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily LoQate
Ashbya (AGD) BOND GPMdb (Mass Spec.) Organelle DB
Aspergillus (AspGD) CYC2008 (complexes) MIPS YPL+
Candida (CGD) Complexome Pfam domains YeastGFP
YGOB DIP YeastRC Structure Prediction (Seattle) YeastRC Public Image Repository
YOGY GeneMANIA


IMP

References cited on this page View Complete Literature Guide for Ccp1p
1) Charizanis C, et al.  (1999) The mitochondrial cytochrome c peroxidase Ccp1 of Saccharomyces cerevisiae is involved in conveying an oxidative stress signal to the transcription factor Pos9 (Skn7). Mol Gen Genet 262(3):437-47
2) Ho PS, et al.  (1984) Kinetics and energetics of intramolecular electron transfer in yeast cytochrome c peroxidase. Biochemistry 23(18):4122-8
3) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41