UTP30/YKR060W Protein Information

Standard Name	Utp30p 1
Systematic Name	Ykr060wp
ORF Classification	Verified
Description	Putative subunit of U3-containing 90S preribosome complex; complex is involved in production of 18S rRNA and assembly of small ribosomal subunit (1, 2, 3)
Name Description	U Three Protein 1

Experimental Data
Molecules/cell	3060 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	274
Molecular Weight (Da)	31,616
Isoelectric Point (pI)	10.39

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Utp30p (InterPro)
Physical Interactions	There are 47 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000005302F \| P36144 MIPS: YKR060W NCBI: 45269705 \| 486523 \| 549622 \| 6322913 \| NP_012986.1 GenBank/EMBL/DDBJ: DAA09211.1 \| AY557907 \| Z28285

Amino Acid Sequence (or in FASTA format)
1 MVESNDIIKS GLAEKALKAL ILQCEENPSL KNDKDIHIII NTGKKMGINR 51 DNIPRIIPLT KYKLFKPRDL NILLITKDPS ALYRETLTKD EHTSELFKEI 101 ISVKNLRRRF KGSKLTQLYK DFDLVVADYR VHHLLPEVLG SRFYHGSKKL 151 PYMIRMSKEV KLKRQQMVEK CDPIYVRAQL RSICKNTSYI PNNDNCLSVR 201 VGYIQKHSIP EILQNIQDTI NFLTDKSKRP QGGVIKGGII SIFVKTSNST 251 SLPIYQFSEA RENQKNEDLS DIKL*

Amino Acid Sequence (or in FASTA format)

       1  MVESNDIIKS GLAEKALKAL ILQCEENPSL KNDKDIHIII NTGKKMGINR
      51  DNIPRIIPLT KYKLFKPRDL NILLITKDPS ALYRETLTKD EHTSELFKEI
     101  ISVKNLRRRF KGSKLTQLYK DFDLVVADYR VHHLLPEVLG SRFYHGSKKL
     151  PYMIRMSKEV KLKRQQMVEK CDPIYVRAQL RSICKNTSYI PNNDNCLSVR
     201  VGYIQKHSIP EILQNIQDTI NFLTDKSKRP QGGVIKGGII SIFVKTSNST
     251  SLPIYQFSEA RENQKNEDLS DIKL*

external links for Utp30p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Candida (CGD)	BioPIXIE	MIPS	YeastGFP
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Utp30p

1)	Samanta MP and Liang S (2003) Predicting protein functions from redundancies in large-scale protein interaction networks. Proc Natl Acad Sci U S A 100(22):12579-83
2)	Grandi P, et al. (2002) 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol Cell 10(1):105-15
3)	Perez-Fernandez J, et al. (2011) Elucidation of the assembly events required for the recruitment of Utp20, Imp4 and Bms1 onto nascent pre-ribosomes. Nucleic Acids Res 39(18):8105-21
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41