GLG1/YKR058W Protein Information

Standard Name	Glg1p
Systematic Name	Ykr058wp
ORF Classification	Verified
Description	Glycogenin glucosyltransferase; self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside; similar to mammalian glycogenin; GLG1 has a paralog, GLG2, that arose from the whole genome duplication (1, 2, 3)
Name Description	Glycogenin-Like Gene 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	616
Molecular Weight (Da)	69,723
Isoelectric Point (pI)	4.07

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Glg1p (InterPro)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 6 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000065C6A6 \| P36143 MIPS: YKR058W NCBI: 189047139 \| 486519 \| 59802651 \| 83578103 \| 902793 \| NP_012984.2 GenBank/EMBL/DDBJ: DAA09209.1 \| U25546 \| Z28283
External Classifications	EC: 2.4.1.186 [Glycogenin glucosyltransferase]

Amino Acid Sequence (or in FASTA format)
1 MYKKLAIATL LYSADYLPGV FALGHQVNKL LEEAGKKGDI ETCLIVTTSL 51 FNGTLSELAK NILQSIYTKI VLVEPLNCQE ESIQKNSENL ALLERPELSF 101 ALIKARLWEL TQFEQVLYLD SDTLPLNKEF LKLFDIMSKQ TTSQVGAIAD 151 IGWPDMFNSG VMMLIPDADT ASVLQNYIFE NTSIDGSDQG ILNQFFNQNC 201 CTDELVKDSF SREWVQLSFT YNVTIPNLGY QSSPAMNYFK PSIKLIHFIG 251 KHKPWSLWSQ KNFIKNEYHD QWNEVYEEFK EEHQLNNEVS KPKISDSDKT 301 ETPETITPVD APPSNEPTTN QEIDTISTVE ENVDNQNAEP VPNSDHSPAP 351 NPVPLDFTKW LTTFINKDHL TNQPVNESRE YSKENDNNII NSSSNRDQES 401 PPNSTQELNS SYSVVSTQAD SDEHQNAEEE DSTTDNASNS GEESHLDDIS 451 TAASSNNNVS NQPDGKNFSN SKENNISVES SPSNPEQKRS TDNIQKPSVS 501 TNDLPDDVEP HTSVDDNIQY LEKDKEGYEE FLPDVYESNA IDNEEEFFDD 551 DARDATEGET KTSAVADKQE DMKLTAEETN QPQQEMPNFK FDWEDSDYLS 601 KVERCFPDDI FEYAVE*

Amino Acid Sequence (or in FASTA format)

       1  MYKKLAIATL LYSADYLPGV FALGHQVNKL LEEAGKKGDI ETCLIVTTSL
      51  FNGTLSELAK NILQSIYTKI VLVEPLNCQE ESIQKNSENL ALLERPELSF
     101  ALIKARLWEL TQFEQVLYLD SDTLPLNKEF LKLFDIMSKQ TTSQVGAIAD
     151  IGWPDMFNSG VMMLIPDADT ASVLQNYIFE NTSIDGSDQG ILNQFFNQNC
     201  CTDELVKDSF SREWVQLSFT YNVTIPNLGY QSSPAMNYFK PSIKLIHFIG
     251  KHKPWSLWSQ KNFIKNEYHD QWNEVYEEFK EEHQLNNEVS KPKISDSDKT
     301  ETPETITPVD APPSNEPTTN QEIDTISTVE ENVDNQNAEP VPNSDHSPAP
     351  NPVPLDFTKW LTTFINKDHL TNQPVNESRE YSKENDNNII NSSSNRDQES
     401  PPNSTQELNS SYSVVSTQAD SDEHQNAEEE DSTTDNASNS GEESHLDDIS
     451  TAASSNNNVS NQPDGKNFSN SKENNISVES SPSNPEQKRS TDNIQKPSVS
     501  TNDLPDDVEP HTSVDDNIQY LEKDKEGYEE FLPDVYESNA IDNEEEFFDD
     551  DARDATEGET KTSAVADKQE DMKLTAEETN QPQQEMPNFK FDWEDSDYLS
     601  KVERCFPDDI FEYAVE*

external links for Glg1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
YGOB	BioPIXIE	MIPS	YeastGFP
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome
	GeneMANIA

References cited on this page View Complete Literature Guide for Glg1p

1)	Mu J, et al. (1996) Initiation of glycogen synthesis in yeast. Requirement of multiple tyrosine residues for function of the self-glucosylating Glg proteins in vivo. J Biol Chem 271(43):26554-60
2)	Cheng C, et al. (1995) Requirement of the self-glucosylating initiator proteins Glg1p and Glg2p for glycogen accumulation in Saccharomyces cerevisiae. Mol Cell Biol 15(12):6632-40
3)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61