RPS21A/YKR057W Protein Information Help

Standard Name Rps21ap
Systematic Name Ykr057wp
Alias Rps25p
ORF Classification Verified
Description Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S21, no bacterial homolog; RPS21A has a paralog, RPS21B, that arose from the whole genome duplication (1, 2, 3)
Name Description Ribosomal Protein of the Small subunit
Gene Product S21A 4 , S21e 3 , S26A 4 , YS25 4
Experimental Data
Molecules/cell 27400 5
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 87
Molecular Weight (Da) 9,746
Isoelectric Point (pI) 5.9

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Rps21ap (InterPro)
Physical Interactions There are 16 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000134E91 | P0C0V8
MIPS: YKR057W
NCBI: 2131127 | 313103683 | 364506117 | 364506155 | 398365233 | 4411 | 486517 | 84028229 | NP_012983.3
GenBank/EMBL/DDBJ: DAA09208.1 | X07811 | Z28282 | Z28283
Amino Acid Sequence (or in FASTA format)
       1  MENDKGQLVE LYVPRKCSAT NRIIKADDHA SVQINVAKVD EEGRAIPGEY
      51  VTYALSGYVR SRGESDDSLN RLAQNDGLLK NVWSYSR*             

external links for Rps21ap
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Aspergillus (AspGD) BioPIXIE MIPS YeastRC Public Image Repository
YGOB CYC2008 (complexes) Pfam domains
YOGY Complexome YeastRC Structure Prediction (Seattle)

GeneMANIA

References cited on this page View Complete Literature Guide for Rps21ap
1) Lecompte O, et al.  (2002) Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. Nucleic Acids Res 30(24):5382-90
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
3) Jenner L, et al.  (2012) Crystal structure of the 80S yeast ribosome. Curr Opin Struct Biol 22(6):759-67
4) Planta RJ and Mager WH  (1998) The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae. Yeast 14(5):471-7
5) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41