RHO4/YKR055W Protein Information

Standard Name	Rho4p
Systematic Name	Ykr055wp
ORF Classification	Verified
Description	Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely to be involved in the establishment of cell polarity (1, 2)
Name Description	Ras HOmolog 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	291
Molecular Weight (Da)	32,185
Isoelectric Point (pI)	6.66

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Rho4p (InterPro)
Physical Interactions	There are 14 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013388C \| Q00246 MIPS: YKR055W NCBI: 218476 \| 397359 \| 398365217 \| 45269709 \| 464610 \| 486513 \| NP_012981.3 \| NM_001179845.3 GenBank/EMBL/DDBJ: DAA09206.1 \| AY557909 \| D10007 \| Z14126 \| Z25734 \| Z28280

Amino Acid Sequence (or in FASTA format)
1 MNTLLFKRKG GNCGNESNIV SQGSPSSSNL PESPGTLDEK NLPRLPTPFA 51 RSLSTIPSYE QMKRTNKLPD YHLKIVVVGD GAVGKTCLLI SYVQGTFPTD 101 YIPTIFENYV TNIEGPNGQI IELALWDTAG QEEYSRLRPL SYTNADVLMV 151 CYSVGSKTSL KNVEDLWFPE VKHFCPSTPI MLVGLKSDLY EADNLSDLVE 201 PSSAESLAKR LGAFAHIQCS ARLKENIDEV FETAIHTLLS DSLYAPREPT 251 HTIKNPFKRN TTRSDIDSST GDTSVSISGT KRLRKNKCII M*

Amino Acid Sequence (or in FASTA format)

       1  MNTLLFKRKG GNCGNESNIV SQGSPSSSNL PESPGTLDEK NLPRLPTPFA
      51  RSLSTIPSYE QMKRTNKLPD YHLKIVVVGD GAVGKTCLLI SYVQGTFPTD
     101  YIPTIFENYV TNIEGPNGQI IELALWDTAG QEEYSRLRPL SYTNADVLMV
     151  CYSVGSKTSL KNVEDLWFPE VKHFCPSTPI MLVGLKSDLY EADNLSDLVE
     201  PSSAESLAKR LGAFAHIQCS ARLKENIDEV FETAIHTLLS DSLYAPREPT
     251  HTIKNPFKRN TTRSDIDSST GDTSVSISGT KRLRKNKCII M*

external links for Rho4p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Candida (CGD)	BioPIXIE	MIPS	YeastGFP
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Rho4p

1)	Doignon F, et al. (1999) The yeast Rgd1p is a GTPase activating protein of the Rho3 and rho4 proteins. FEBS Lett 459(3):458-62
2)	Madden K and Snyder M (1998) Cell polarity and morphogenesis in budding yeast. Annu Rev Microbiol 52():687-744
3)	Matsui Y and Toh-e A (1992) Isolation and characterization of two novel ras superfamily genes in Saccharomyces cerevisiae. Gene 114(1):43-9