TRK2/YKR050W Protein Information Help

Standard Name Trk2p 1, 2
Systematic Name Ykr050wp
Alias Rpd2p
ORF Classification Verified
Description Component of the Trk1p-Trk2p potassium transport system; TRK2 has a paralog, TRK1, that arose from the whole genome duplication (1, 3, 4)
Name Description TRansport of potassium (K)
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 889
Molecular Weight (Da) 101,086
Isoelectric Point (pI) 10.36

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Trk2p (InterPro)
Transmembrane Domains There are 10 total predicted transmembrane domains (TMHMM)
Physical Interactions There are 3 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI00001373C0 | P28584
MIPS: YKR050W
NCBI: 136232 | 173033 | 486503 | 6322903 | NP_012976.1
GenBank/EMBL/DDBJ: DAA09201.1 | M65215 | Z28275
External Classifications TC: 2.A.38.2
Amino Acid Sequence (or in FASTA format)
 
       1  MPTAKRTSSR ASLALPFQLR LVHKKSWGHR LRDFISGFLK SCRPIAKYVF
      51  PNFIVVHYIY LITLSIIGSI LLYPCKNTAF IDVLFLAAGA STQGGLATKS
     101  TNDFNLYQQI VVYVITLLST PILIHGFLAF VRLYWFERYF DNIRDISKQN
     151  FKLRRTMTLQ QRELSGSSGN AARSRSFKDN LFRGKFVSRE DPRQSASDVP
     201  MDSPDTSALS SISPLNVSSS KEESSDTQSS PPNFSSKRQP SDVDPRDIYK
     251  SIMMLQKQQE KSNANSTDSF SSETNGPAFI VQERHERRAP HCSLKRHSVL
     301  PSSQELNKLA QTKSFQKLLG LRRDEGDHDY FDGAPHKYMV TKKKKISRTQ
     351  SCNIPTYTAS PSPKTSGQVV ENHRNLAKSA PSSFVDEEMS FSPQESLNLQ
     401  FQAHPPKPKR REGDIGHPFT RTMSTNYLSW QPTFGRNSVF IGLTKQQKEE
     451  LGGVEYRALR LLCCILMVYY IGFNILAFVT IVPWACTRHH YSEIIRRNGV
     501  SPTWWGFFTA MSAFSNLGLS LTADSMVSFD TAPYPLIFMM FFIIIGNTGF
     551  PIMLRFIIWI MFKTSRDLSQ FKESLGFLLD HPRRCFTLLF PSGPTWWLFT
     601  TLVVLNATDW ILFIILDFNS AVVRQVAKGY RALMGLFQSV CTRTAGFNVV
     651  DLSKLHPSIQ VSYMLMMYVS VLPLAISIRR TNVYEEQSLG LYDSGQDDEN
     701  ITHEDDIKET DHDGESEERD TVSTKSKPKK QSPKSFVGAH LRRQLSFDLW
     751  YLFLGLFIIC ICEGRKIEDV NKPDFNVFAI LFEVVSAYGT VGLSLGYPNT
     801  NTSLSAQFTV LSKLVIIAML IRGRNRGLPY TLDRAIMLPS DKLEQIDRLQ
     851  DMKAKGKLLA KVGEDPMTTY VKKRSHKLKK IATKFWGKH*

external links for Trk2p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Candida (CGD) BioPIXIE MIPS
Candida (CandidaDB) CYC2008 (complexes) Pfam domains
YGOB Complexome TCDB
YOGY DIP YeastRC Structure Prediction (Seattle)

GeneMANIA

References cited on this page View Complete Literature Guide for Trk2p
1) Ko CH, et al.  (1990) TRK2 is required for low affinity K+ transport in Saccharomyces cerevisiae. Genetics 125(2):305-12
2) Petitjean, A. and Tatchell, K.  (1989) Personal Communication, Mortimer Map Edition 10
3) Ko CH and Gaber RF  (1991) TRK1 and TRK2 encode structurally related K+ transporters in Saccharomyces cerevisiae. Mol Cell Biol 11(8):4266-73
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61