SAP190/YKR028W Protein Information Help

Standard Name Sap190p 1
Systematic Name Ykr028wp
ORF Classification Verified
Description Protein that forms a complex with the Sit4p protein phosphatase; required for Sit4p function; member of a family of similar proteins including Sap4p, Sap155p, and Sap185p; SAP190 has a paralog, SAP185, that arose from the whole genome duplication (1, 2)
Name Description Sit4 Associated Protein 1
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 1,033
Molecular Weight (Da) 117,098
Isoelectric Point (pI) 3.97

Click on image for expanded interactive view
pbrowse

Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Sap190p (InterPro)
Physical Interactions There are 25 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000052E63 | P36123
MIPS: YKR028W
NCBI: 1345144 | 1710848 | 330443662 | 486457 | NP_012953.2 | NM_001179818.2
GenBank/EMBL/DDBJ: AAC49304.1 | CAA82100.1 | DAA09183.2 | U50561 | Z28253
Amino Acid Sequence (or in FASTA format)
       1  MSGSFWKFGQ DYSIESPVSK ILNSAFIKIN KDQDDDVPTG TCEENIADDE
      51  DNSSHDYAAS EDNVVNENEE KEEENTLPTT ESEYENYRPN LDVLDDLLDD
     101  DELYTELMCS NFKLLIFLKY PDVLSKLIEY VTNEKILDEE TDSAKKPEII
     151  EGVNDHPILI ERDRKDKKED AEEGGDSEET TNDSDHDSGD ERSVDSEETS
     201  ITLPPESEEQ VETRRARIAA EILSADVWPI SAAIMQNKDL LGRLWSILDH
     251  PAPLPIPAST YFMKINERLL DMDITGMLEF ILSRDSLVAR FLTHVDNPSL
     301  MDFLLKVIST DKPDSPTGVI KILKSQELIP KLLDHLNPEY GISTQSAAGD
     351  FIKAFVTLST NSSNELASGI GPNELTRQLV SEEMIEKLIK IMLKGGTSLS
     401  NGVGIIIELI RKNNSDYDFI QLVYTTLESH PPTDRDPIHL IHLVKLFAKH
     451  MPDFADMLDK TKLPLMEMPF GNIEPLGFER FKICELIAEL LHCSNMTLLN
     501  EPNGEMIAQE RDIERAKELE TSTEKENITA IVDNKSSYYD KDCVEKDITE
     551  NLGALQINNQ GSEEDELNDT GVSSVKLDVK SDAKVVEGLE NDASGVELYD
     601  ETLSDTESVR ECLREKPLVG DRLKIALEDT KILISILDMF TEFPWNNFLH
     651  NVIFDIAQQI FNGPLKTGYN RFLLKDYLVD AYLTKKIVDA DKACQDYEKK
     701  TGLRYGYMGH LTLVAEEISK FKEYIDEMKL TFCNTAVSDR LEEPFWKEYS
     751  ETILADTREK YNTVLGDFGN DQESDDDVIR NSDSEDIIGD TEGNENYGNG
     801  ENDELLSNGH DSGNMDLYYN FNNNENEENE EDYAEYSDVD NKNYYNNVET
     851  NDDDYDSDDG KSKSAESEFT DKISEHRDGN SLYNEDNDEN GSDKWTSGTS
     901  LFPPDHFPSR SQPSDPKLQD QNIFHHQFDF EGVGDDDDYM DPNDDGQSYA
     951  RPGNPLYTTP KTPPRPKTIL FNSLSALDNN GEDEEVALGT SVDDRMDNEI
    1001  SSDEEDSEDE DEENDMGNEE GYSLYRSRSK EAF*                 

external links for Sap190p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily LoQate
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Candida (CGD) CYC2008 (complexes) MIPS YeastGFP
YGOB Complexome Pfam domains
YOGY DIP YeastRC Structure Prediction (Seattle)

GeneMANIA


IMP

References cited on this page View Complete Literature Guide for Sap190p
1) Luke MM, et al.  (1996) The SAP, a new family of proteins, associate and function positively with the SIT4 phosphatase. Mol Cell Biol 16(6):2744-55
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61