DBP7/YKR024C Protein Information Help

Standard Name Dbp7p 1
Systematic Name Ykr024cp
ORF Classification Verified
Description Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis; essential for growth under anaerobic conditions (1, 2)
Name Description Dead Box Protein 1
Experimental Data
Molecules/cell 1460 3
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 742
Molecular Weight (Da) 83,308
Isoelectric Point (pI) 10.04

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Dbp7p (InterPro)
Physical Interactions There are 30 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000128F2E | P36120
MIPS: YKR024C
NCBI: 486449 | 549597 | 6322876 | NP_012949.1
GenBank/EMBL/DDBJ: DAA09179.1 | Z28249
External Classifications EC: 3.6.1.- [Hydrolases acting on acid anhydrides in phosphorous-containing anhydrides]
EC: 3.6.4.13 [RNA helicase]
Amino Acid Sequence (or in FASTA format)
 
       1  MSDEDSMLLN FTTNEDTAGS SYKQAAKVTG GRWKDRRRMK MKLEGKTVSR
      51  KRKANTTGDE GIIPGRGENS IKKLHKESSY SSEEQEKYKG RNAHNTQGRT
     101  LPADSQFVSS LFTSNREITT AVNTNIHDEN VAINPSNAPL KGDQFASLGV
     151  SSLLVSHLEQ KMRIKKPTSI QKQAIPQIIG NAGKNDFFIH AQTGSGKTLS
     201  YLLPIISTIL NMDTHVDRTS GAFALVIAPT RELASQIYHV CSTLVSCCHY
     251  LVPCLLIGGE RKKSEKARLR KGCNFIIGTP GRVLDHLQNT KVIKEQLSQS
     301  LRYIVLDEGD KLMELGFDET ISEIIKIVHD IPINSEKFPK LPHKLVHMLC
     351  SATLTDGVNR LRNVALKDYK LISNGTKKDS DIVTVAPDQL LQRITIVPPK
     401  LRLVTLAATL NNITKDFIAS GQQSKTLRTI VFVSCSDSVE FHYDAFSGSD
     451  GHHKNLTGDS VRLLTKGNTM FPCFSDSRDP DVVIYKLHGS LSQQMRTSTL
     501  QHFARDNEAT KGKHLIMFCT DVASRGLDLP HVGSVIELDP PFAVEDHLHR
     551  VGRTARAGEK GESLLFLLPG EEEKYMDYIQ PYHPMGWELL KFDKEILMPA
     601  FKDVNVNRND KFIRKDEKSS KNKDVGDKEY EWDTNATTWH LNIERRVVGD
     651  SAFKNLAVKG FISHVRAYAT HISQEKKFFN VKFLHLGHLA KSFGLRERPK
     701  AMGLQSSKDG NSEKKPTKEN SKNKMFRMAR MAEKQIASEF NY*

external links for Dbp7p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Candida (CGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CandidaDB) CYC2008 (complexes) Pfam domains
YGOB Complexome YeastRC Structure Prediction (Seattle)
YOGY DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Dbp7p
1) Daugeron MC and Linder P  (1998) Dbp7p, a putative ATP-dependent RNA helicase from Saccharomyces cerevisiae, is required for 60S ribosomal subunit assembly. RNA 4(5):566-81
2) Snoek IS and Steensma HY  (2006) Why does Kluyveromyces lactis not grow under anaerobic conditions? Comparison of essential anaerobic genes of Saccharomyces cerevisiae with the Kluyveromyces lactis genome. FEMS Yeast Res 6(3):393-403
3) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41