YKL222C Protein Information Help

Systematic Name Ykl222cp
ORF Classification Verified
Description Protein of unknown function that may interact with ribosomes, based on co-purification experiments; similar to transcriptional regulators from the zinc cluster (binuclear cluster) family; null mutant is sensitive to caffeine (1, 2)
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 705
Molecular Weight (Da) 82,247
Isoelectric Point (pI) 8.1

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Ykl222cp (InterPro)
Physical Interactions There are 1 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000013B771 | P35995
MIPS: YKL222C
NCBI: 473127 | 486399 | 549760 | 6322627 | NP_012700.1
GenBank/EMBL/DDBJ: DAA08947.1 | X75950 | Z28222
Amino Acid Sequence (or in FASTA format)
 
       1  MKNTELSQKK KLDRQSRRKP AKSCHFCRVR KLKCDRVRPF CGSCSSRNRK
      51  QCEYKENTSA MEDQLRKKYR RCSKLEMARR IEELESQLTK QSQPNIHEGQ
     101  NPLSNMRYLS SKHNRHILYG PTSYRAILAT QTDTFAKYRE EIWQVLKLSR
     151  NNWKREHHYS TLSEISSIET APPHSGSPSV IEYLCESLPN YEVLCEYLTD
     201  FFASDFYDSY QIVHKEKVLR DLQDCFVKGP RSHKTGQHTI ISLNLDSKKN
     251  YYKVGVMTAI MCLASHPKEV PEAIEVFHKV LTSFVSAKVF YTERVQFLFL
     301  RYLYINVAGL DGGDQSHCIF IHGLTIDTAI HMGLNEDLRR LYLSKNHPIE
     351  EIPYLERLWL WILFTDVKIS LSTGIPVRIN DDFVNKVRLE NYSSSGDILL
     401  YKTTLRLRNI MKQIHAREKP PDIPLIIEDL KKFTIKMFKP LDFYLNASNL
     451  NGNEFTELQL WHATLHMIGS LSNLYTLTHQ DFDARIFNFS VLAPLNSLHL
     501  CFNVLETYFE LDNSKLSSKS LCLSKKWPHL NNALFLIYVN AFRALIQIYT
     551  IFLQYMENKD IQLFIQRNSS ALTYSICPGD FEGPHNKCIS LKIAFKEMEN
     601  IFDHIHQEKL KPLTQIWQNS YYFSIIISME KIGRRAFNKG MKNIDEGPET
     651  ENDATENSLT TILNDLEGPL EDFSENFIDD ILGSPSAFFD TAISGWSNFE
     701  DFFSR*

external links for Ykl222cp
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
YGOB BioPIXIE MIPS YeastRC Public Image Repository
YOGY CYC2008 (complexes) Pfam domains

Complexome YeastRC Structure Prediction (Seattle)

DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Ykl222cp
1) Akache B, et al.  (2001) Phenotypic analysis of genes encoding yeast zinc cluster proteins. Nucleic Acids Res 29(10):2181-90
2) Fleischer TC, et al.  (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307