HYM1/YKL189W Protein Information Help

Standard Name Hym1p 1
Systematic Name Ykl189wp
ORF Classification Verified
Description Component of the RAM signaling network; is involved in regulation of Ace2p activity and cellular morphogenesis, interacts with Kic1p and Sog2p, localizes to sites of polarized growth during budding and during the mating response (1, 2)
Experimental Data
Molecules/cell 1280 3
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 399
Molecular Weight (Da) 45,853
Isoelectric Point (pI) 8.52

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Hym1p (InterPro)
Physical Interactions There are 18 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000012D010 | P32464
MIPS: YKL189W
NCBI: 296989 | 395236 | 418609 | 486335 | 6322659 | NP_012732.1 | NM_001179755.1
GenBank/EMBL/DDBJ: CAA49422.1 | CAA52249.1 | CAA82032.1 | DAA08977.1 | X69765 | X74151 | Z28189
Amino Acid Sequence (or in FASTA format)
       1  MFKKYKNQDL DMAFWWKKNP KTPSDYARLI IEQLNKFSSP SLTQDNKRKV
      51  QEECTKYLIG TKHFIVGDTD PHPTPEAIDE LYTAMHRADV FYELLLHFVD
     101  LEFEARRECM LIFSICLGYS KDNKFVTVDY LVSQPKTISL MLRTAEVALQ
     151  QKGCQDIFLT VGNMIIECIK YEQLCRIILK DPQLWKFFEF AKLGNFEIST
     201  ESLQILSAAF TAHPKLVSKE FFSNEINIIR FIKCINKLMA HGSYVTKRQS
     251  TKLLASLIVI RSNNALMNIY INSPENLKLI MTLMTDKSKN LQLEAFNVFK
     301  VMVANPRKSK PVFDILVKNR DKLLTYFKTF GLDSQDSTFL DEREFIVQEI
     351  DSLPRIISST TEVSNNNASS SNVASITSPS SVMNNQSSIL THSTSPDSR*

external links for Hym1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily LoQate
Ashbya (AGD) BOND GPMdb (Mass Spec.) Organelle DB
Candida (CGD) CYC2008 (complexes) MIPS YPL+
YGOB Complexome Pfam domains YeastGFP
YOGY DIP YeastRC Structure Prediction (Seattle) YeastRC Public Image Repository

GeneMANIA


IMP

References cited on this page View Complete Literature Guide for Hym1p
1) Karos M and Fischer R  (1999) Molecular characterization of HymA, an evolutionarily highly conserved and highly expressed protein of Aspergillus nidulans. Mol Gen Genet 260(6):510-21
2) Nelson B, et al.  (2003) RAM: a conserved signaling network that regulates Ace2p transcriptional activity and polarized morphogenesis. Mol Biol Cell 14(9):3782-803
3) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41