MTR2/YKL186C Protein Information

Standard Name	Mtr2p 1, 2
Systematic Name	Ykl186cp
ORF Classification	Verified
Description	mRNA transport regulator, essential nuclear protein; Mex67p and Mtr2p form a mRNA export complex which binds to RNA (1)
Name Description	Mrna TRansport 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	184
Molecular Weight (Da)	20,783
Isoelectric Point (pI)	7.93

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Mtr2p (InterPro)
Physical Interactions	There are 35 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000012F82B \| P34232 MIPS: YKL186C NCBI: 33357686 \| 395239 \| 45271000 \| 465687 \| 486329 \| 6322662 \| 957277 \| NP_012735.1 GenBank/EMBL/DDBJ: DAA08980.1 \| AY558555 \| S77467 \| X74151 \| Z28186

Amino Acid Sequence (or in FASTA format)
1 MNTNSNTMVM NDANQAQITA TFTKKILAHL DDPDSNKLAQ FVQLFNPNNC 51 RIIFNATPFA QATVFLQMWQ NQVVQTQHAL TGVDYHAIPG SGTLICNVNC 101 KVRFDESGRD KMGQDATVPI QPNNTGNRNR PNDMNKPRPL WGPYFGISLQ 151 LIIDDRIFRN DFNGVISGFN YNMVYKPEDS LLKI*

Amino Acid Sequence (or in FASTA format)

       1  MNTNSNTMVM NDANQAQITA TFTKKILAHL DDPDSNKLAQ FVQLFNPNNC
      51  RIIFNATPFA QATVFLQMWQ NQVVQTQHAL TGVDYHAIPG SGTLICNVNC
     101  KVRFDESGRD KMGQDATVPI QPNNTGNRNR PNDMNKPRPL WGPYFGISLQ
     151  LIIDDRIFRN DFNGVISGFN YNMVYKPEDS LLKI*

external links for Mtr2p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Candida (CGD)	BioPIXIE	MIPS	YeastGFP
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
YGOB	Complexome
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Mtr2p

1)	Kadowaki T, et al. (1994) Nuclear mRNA accumulation causes nucleolar fragmentation in yeast mtr2 mutant. Mol Biol Cell 5(11):1253-63
2)	Kadowaki T, et al. (1994) Isolation and characterization of Saccharomyces cerevisiae mRNA transport-defective (mtr) mutants. J Cell Biol 126(3):649-59