GPM1/YKL152C Protein Information

Standard Name	Gpm1p 1
Systematic Name	Ykl152cp
ORF Classification	Verified
Description	Tetrameric phosphoglycerate mutase, mediates the conversion of 3-phosphoglycerate to 2-phosphoglycerate during glycolysis and the reverse reaction during gluconeogenesis (2, 3)
Name Description	Glycerate PhosphoMutase 1

Experimental Data
Molecules/cell	172000 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	247
Molecular Weight (Da)	27,608
Isoelectric Point (pI)	9.65

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Gpm1p (InterPro)
Physical Interactions	There are 55 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000052EDE \| P00950 MIPS: YKL152C NCBI: 1326042 \| 157836868 \| 157836869 \| 2624630 \| 2624631 \| 2624632 \| 2624633 \| 299358 \| 3660055 \| 3660056 \| 3660057 \| 3660058 \| 3660059 \| 3660060 \| 3660061 \| 3660062 \| 3749 \| 407495 \| 433552073 \| 4558238 \| 4558239 \| 4558240 \| 4558241 \| 4558243 \| 4558244 \| 4558245 \| 486265 \| 548534 \| 5542362 \| 5542363 \| 6322697 \| NP_012770.1 \| NM_001179718.1 GenBank/EMBL/DDBJ: DAA09011.1 \| S57976 \| X06408 \| X58789 \| Z26877 \| Z28152
External Classifications	EC: 5.4.2.1 [Phosphoglycerate mutase]

Amino Acid Sequence (or in FASTA format)
1 MPKLVLVRHG QSEWNEKNLF TGWVDVKLSA KGQQEAARAG ELLKEKKVYP 51 DVLYTSKLSR AIQTANIALE KADRLWIPVN RSWRLNERHY GDLQGKDKAE 101 TLKKFGEEKF NTYRRSFDVP PPPIDASSPF SQKGDERYKY VDPNVLPETE 151 SLALVIDRLL PYWQDVIAKD LLSGKTVMIA AHGNSLRGLV KHLEGISDAD 201 IAKLNIPTGI PLVFELDENL KPSKPSYYLD PEAAAAGAAA VANQGKK*

Amino Acid Sequence (or in FASTA format)

       1  MPKLVLVRHG QSEWNEKNLF TGWVDVKLSA KGQQEAARAG ELLKEKKVYP
      51  DVLYTSKLSR AIQTANIALE KADRLWIPVN RSWRLNERHY GDLQGKDKAE
     101  TLKKFGEEKF NTYRRSFDVP PPPIDASSPF SQKGDERYKY VDPNVLPETE
     151  SLALVIDRLL PYWQDVIAKD LLSGKTVMIA AHGNSLRGLV KHLEGISDAD
     201  IAKLNIPTGI PLVFELDENL KPSKPSYYLD PEAAAAGAAA VANQGKK*

external links for Gpm1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Candida (CGD)	BioPIXIE	MIPS	YeastGFP
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA
	YeastRC Mass Spec (Seattle)

References cited on this page View Complete Literature Guide for Gpm1p

1)	Heinisch J, et al. (1991) Sequence and localization of the gene encoding yeast phosphoglycerate mutase. Curr Genet 20(1-2):167-71
2)	Rodicio R, et al. (1993) Transcriptional control of yeast phosphoglycerate mutase-encoding gene. Gene 125(2):125-33
3)	Lam KB and Marmur J (1977) Isolation and characterization of Saccharomyces cerevisiae glycolytic pathway mutants. J Bacteriol 130(2):746-9
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41