GPM1/YKL152C Protein Information Help

Standard Name Gpm1p 1
Systematic Name Ykl152cp
ORF Classification Verified
Description Tetrameric phosphoglycerate mutase; mediates the conversion of 3-phosphoglycerate to 2-phosphoglycerate during glycolysis and the reverse reaction during gluconeogenesis (2, 3)
Name Description Glycerate PhosphoMutase 1
Experimental Data
Molecules/cell 172000 4
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 247
Molecular Weight (Da) 27,608
Isoelectric Point (pI) 9.65

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Gpm1p (InterPro)
Physical Interactions There are 60 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000052EDE | P00950
MIPS: YKL152C
NCBI: 1326042 | 157836868 | 2624630 | 299358 | 3749 | 407495 | 486265 | 548534 | 5542362 | 6322697 | NP_012770.1 | NM_001179718.1
GenBank/EMBL/DDBJ: AAB26026.1 | CAA29698.1 | CAA41595.1 | CAA81501.1 | CAA81994.1 | DAA09011.1 | S57976 | X06408 | X58789 | Z26877 | Z28152
External Classifications EC: 5.4.2.1 [Phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)]
EC: 5.4.2.11 [Phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)]
Amino Acid Sequence (or in FASTA format)
       1  MPKLVLVRHG QSEWNEKNLF TGWVDVKLSA KGQQEAARAG ELLKEKKVYP
      51  DVLYTSKLSR AIQTANIALE KADRLWIPVN RSWRLNERHY GDLQGKDKAE
     101  TLKKFGEEKF NTYRRSFDVP PPPIDASSPF SQKGDERYKY VDPNVLPETE
     151  SLALVIDRLL PYWQDVIAKD LLSGKTVMIA AHGNSLRGLV KHLEGISDAD
     201  IAKLNIPTGI PLVFELDENL KPSKPSYYLD PEAAAAGAAA VANQGKK*  

external links for Gpm1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily LoQate
Ashbya (AGD) BOND GPMdb (Mass Spec.) Organelle DB
Candida (CGD) CYC2008 (complexes) MIPS YPL+
YGOB Complexome Pfam domains YeastGFP
YOGY DIP YeastRC Structure Prediction (Seattle) YeastRC Public Image Repository

GeneMANIA


IMP


YeastRC Mass Spec (Seattle)

References cited on this page View Complete Literature Guide for Gpm1p
1) Heinisch J, et al.  (1991) Sequence and localization of the gene encoding yeast phosphoglycerate mutase. Curr Genet 20(1-2):167-71
2) Rodicio R, et al.  (1993) Transcriptional control of yeast phosphoglycerate mutase-encoding gene. Gene 125(2):125-33
3) Lam KB and Marmur J  (1977) Isolation and characterization of Saccharomyces cerevisiae glycolytic pathway mutants. J Bacteriol 130(2):746-9
4) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41