MAE1/YKL029C Protein Information Help

Standard Name Mae1p
Systematic Name Ykl029cp
ORF Classification Verified
Description Mitochondrial malic enzyme, catalyzes the oxidative decarboxylation of malate to pyruvate, which is a key intermediate in sugar metabolism and a precursor for synthesis of several amino acids (1)
Name Description MAlic Enzyme 1
Experimental Data
Molecules/cell 10500 2
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 669
Molecular Weight (Da) 74,375
Isoelectric Point (pI) 8.19

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Mae1p (InterPro)
Physical Interactions There are 75 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000012EBB9 | P36013
MIPS: YKL029C
NCBI: 486030 | 547888 | 6322823 | NP_012896.1
GenBank/EMBL/DDBJ: DAA09125.1 | Z28029
External Classifications EC: 1.1.1.38 [Malate dehydrogenase (oxaloacetate-decarboxylating)]
Amino Acid Sequence (or in FASTA format)
 
       1  MLRTRLSVSV AARSQLTRSL TASRTAPLRR WPIQQSRLYS SNTRSHKATT
      51  TRENTFQKPY SDEEVTKTPV GSRARKIFEA PHPHATRLTV EGAIECPLES
     101  FQLLNSPLFN KGSAFTQEER EAFNLEALLP PQVNTLDEQL ERSYKQLCYL
     151  KTPLAKNDFM TSLRVQNKVL YFALIRRHIK ELVPIIYTPT EGDAIAAYSH
     201  RFRKPEGVFL DITEPDSIEC RLATYGGDKD VDYIVVSDSE GILGIGDQGI
     251  GGVRIAISKL ALMTLCGGIH PGRVLPVCLD VGTNNKKLAR DELYMGNKFS
     301  RIRGKQYDDF LEKFIKAVKK VYPSAVLHFE DFGVKNARRL LEKYRYELPS
     351  FNDDIQGTGA VVMASLIAAL KHTNRDLKDT RVLIYGAGSA GLGIADQIVN
     401  HMVTHGVDKE EARKKIFLMD RRGLILQSYE ANSTPAQHVY AKSDAEWAGI
     451  NTRSLHDVVE NVKPTCLVGC STQAGAFTQD VVEEMHKHNP RPIIFPLSNP
     501  TRLHEAVPAD LMKWTNNNAL VATGSPFPPV DGYRISENNN CYSFPGIGLG
     551  AVLSRATTIT DKMISAAVDQ LAELSPLREG DSRPGLLPGL DTITNTSARL
     601  ATAVILQALE EGTARIEQEQ VPGGAPGETV KVPRDFDECL QWVKAQMWEP
     651  VYRPMIKVQH DPSVHTNQL*

external links for Mae1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Aspergillus (AspGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CGD) CYC2008 (complexes) Pfam domains
Candida (CandidaDB) Complexome YeastRC Structure Prediction (Seattle)
YGOB DIP

YOGY GeneMANIA

References cited on this page View Complete Literature Guide for Mae1p
1) Boles E, et al.  (1998) Identification and characterization of MAE1, the Saccharomyces cerevisiae structural gene encoding mitochondrial malic enzyme. J Bacteriol 180(11):2875-82
2) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41