TFA1/YKL028W Protein Information Help

Standard Name Tfa1p 1
Systematic Name Ykl028wp
ORF Classification Verified
Description TFIIE large subunit; involved in recruitment of RNA polymerase II to the promoter, activation of TFIIH, and promoter opening (1, 2, 3)
Name Description Transcription Factor a, subunit 1 1
Experimental Data
Molecules/cell 35900 4
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 482
Molecular Weight (Da) 54,741
Isoelectric Point (pI) 4.22

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Tfa1p (InterPro)
Transmembrane Domains There are 1 total predicted transmembrane domains (TMHMM)
Signal Peptide(s) There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions There are 63 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000005304A | P36100
MIPS: YKL028W
NCBI: 398364645 | 486027 | 549038 | 607958 | NP_012897.3 | NM_001179594.3
GenBank/EMBL/DDBJ: AAA62665.1 | CAA81863.1 | DAA09126.1 | U12825 | Z28028
Amino Acid Sequence (or in FASTA format)
       1  MDRPIDDIVK NLLKFVVRGF YGGSFVLVLD AILFHSVLAE DDLKQLLSIN
      51  KTELGPLIAR LRSDRLISIH KQREYPPNSK SVERVYYYVK YPHAIDAIKW
     101  KVHQVVQRLK DDLDKNSEPN GYMCPICLTK YTQLEAVQLL NFDRTEFLCS
     151  LCDEPLVEDD SGKKNKEKQD KLNRLMDQIQ PIIDSLKKID DSRIEENTFE
     201  IALARLIPPQ NQSHAAYTYN PKKGSTMFRP GDSAPLPNLM GTALGNDSSR
     251  RAGANSQATL HINITTASDE VAQRELQERQ AEEKRKQNAV PEWHKQSTIG
     301  KTALGRLDNE EEFDPVVTAS AMDSINPDNE PAQETSYQNN RTLTEQEMEE
     351  RENEKTLNDY YAALAKKQAK LNKEEEEEEE EEEDEEEEEE EEMEDVMDDN
     401  DETARENALE DEFEDVTDTA GTAKTESNTS NDVKQESIND KTEDAVNATA
     451  TASGPSANAK PNDGDDDDDD DDDEMDIEFE DV*                  

external links for Tfa1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily LoQate
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Aspergillus (AspGD) CYC2008 (complexes) MIPS YeastGFP
Candida (CGD) Complexome Pfam domains YeastRC Public Image Repository
YGOB DIP YeastRC Structure Prediction (Seattle)
YOGY GeneMANIA


IMP

References cited on this page View Complete Literature Guide for Tfa1p
1) Feaver WJ, et al.  (1994) Yeast TFIIE. Cloning, expression, and homology to vertebrate proteins. J Biol Chem 269(44):27549-53
2) Lee TI and Young RA  (2000) Transcription of eukaryotic protein-coding genes. Annu Rev Genet 34:77-137
3) Orphanides G, et al.  (1996) The general transcription factors of RNA polymerase II. Genes Dev 10(21):2657-83
4) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41