MRT4/YKL009W Protein Information

Standard Name	Mrt4p
Systematic Name	Ykl009wp
ORF Classification	Verified
Description	Protein involved in mRNA turnover and ribosome assembly, localizes to the nucleolus (1, 2, 3)
Name Description	mRNA Turnover 4 1

Experimental Data
Molecules/cell	18200 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	236
Molecular Weight (Da)	27,058
Isoelectric Point (pI)	9.05

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Mrt4p (InterPro)
Physical Interactions	There are 189 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000053229 \| P33201 MIPS: YKL009W NCBI: 1680603 \| 263500 \| 465665 \| 485985 \| 6322843 \| NP_012916.1 GenBank/EMBL/DDBJ: DAA09147.1 \| S53418 \| S59773 \| X61398 \| Z28009

Amino Acid Sequence (or in FASTA format)
1 MPRSKRSKLV TLAQTDKKGR ENKERIFDEV REALDTYRYV WVLHLDDVRT 51 PVLQEIRTSW AGSKLIMGKR KVLQKALGEK REEEYKENLY QLSKLCSGVT 101 GLLFTDEDVN TVKEYFKSYV RSDYSRPNTK APLTFTIPEG IVYSRGGQIP 151 AEEDVPMIHS LEPTMRNKFE IPTKIKAGKI TIDSPYLVCT EGEKLDVRQA 201 LILKQFGIAA SEFKVKVSAY YDNDSSTVES TNINME*

Amino Acid Sequence (or in FASTA format)

       1  MPRSKRSKLV TLAQTDKKGR ENKERIFDEV REALDTYRYV WVLHLDDVRT
      51  PVLQEIRTSW AGSKLIMGKR KVLQKALGEK REEEYKENLY QLSKLCSGVT
     101  GLLFTDEDVN TVKEYFKSYV RSDYSRPNTK APLTFTIPEG IVYSRGGQIP
     151  AEEDVPMIHS LEPTMRNKFE IPTKIKAGKI TIDSPYLVCT EGEKLDVRQA
     201  LILKQFGIAA SEFKVKVSAY YDNDSSTVES TNINME*

external links for Mrt4p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Mrt4p

1)	Zuk D, et al. (1999) Temperature-sensitive mutations in the Saccharomyces cerevisiae MRT4, GRC5, SLA2 and THS1 genes result in defects in mRNA turnover. Genetics 153(1):35-47
2)	Harnpicharnchai P, et al. (2001) Composition and functional characterization of yeast 66S ribosome assembly intermediates. Mol Cell 8(3):505-15
3)	Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41