MET14/YKL001C Protein Information

Standard Name	Met14p 1
Systematic Name	Ykl001cp
ORF Classification	Verified
Description	Adenylylsulfate kinase, required for sulfate assimilation and involved in methionine metabolism (2)
Name Description	METhionine requiring 1

Experimental Data
Molecules/cell	2170 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	202
Molecular Weight (Da)	23,060
Isoelectric Point (pI)	8.18

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Met14p (InterPro)
Physical Interactions	There are 11 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000012DC33 \| Q02196 MIPS: YKL001C NCBI: 235815 \| 3529 \| 398364837 \| 400121 \| 45270412 \| 485973 \| 511139 \| NP_012925.3 \| NM_001179567.3 GenBank/EMBL/DDBJ: DAA09156.1 \| AY558261 \| S55315 \| X57990 \| X65124 \| Z28001
External Classifications	EC: 2.7.1.25 [Adenylyl-sulfate kinase]

Amino Acid Sequence (or in FASTA format)
1 MATNITWHPN LTYDERKALR KQDGCTIWLT GLSASGKSTI ACALEQLLLQ 51 KNLSAYRLDG DNIRFGLNKD LGFSEKDRNE NIRRISEVSK LFADSCAISI 101 TSFISPYRVD RDRARELHKE AGLKFIEIFV DVPLEVAEQR DPKGLYKKAR 151 EGVIKEFTGI SAPYEAPKAP ELHLRTDQKT VEECATIIYE YLISEKIIRK 201 HL*

Amino Acid Sequence (or in FASTA format)

       1  MATNITWHPN LTYDERKALR KQDGCTIWLT GLSASGKSTI ACALEQLLLQ
      51  KNLSAYRLDG DNIRFGLNKD LGFSEKDRNE NIRRISEVSK LFADSCAISI
     101  TSFISPYRVD RDRARELHKE AGLKFIEIFV DVPLEVAEQR DPKGLYKKAR
     151  EGVIKEFTGI SAPYEAPKAP ELHLRTDQKT VEECATIIYE YLISEKIIRK
     201  HL*

external links for Met14p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Met14p

1)	Masselot M and De Robichon-Szulmajster H (1975) Methionine biosynthesis in Saccharomyces cerevisiae. I. Genetical analysis of auxotrophic mutants. Mol Gen Genet 139(2):121-32
2)	Donalies UE and Stahl U (2002) Increasing sulphite formation in Saccharomyces cerevisiae by overexpression of MET14 and SSU1. Yeast 19(6):475-84
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41