YPS6/YIR039C Protein Information

Standard Name	Yps6p
Systematic Name	Yir039cp
ORF Classification	Verified
Description	Putative GPI-anchored aspartic protease, member of the yapsin family of proteases involved in cell wall growth and maintenance (1, 2)
Name Description	YaPSin

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	537
Molecular Weight (Da)	58,213
Isoelectric Point (pI)	3.95

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Yps6p (InterPro)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 3 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013B485 \| P40583 MIPS: YIR039C NCBI: 398364761 \| 557845 \| 600456 \| 731925 \| NP_012305.3 GenBank/EMBL/DDBJ: DAA08586.1 \| Z38061 \| Z46902
External Classifications	EC: 3.4.23.- [Aspartic Endopeptidases]

Amino Acid Sequence (or in FASTA format)
1 MQLISILSLL SSLMCSLTVL GSSASSYVKF PVQKLADIIN ICTQDVSTVF 51 KRNEVLNTTV INGIGVYVVK MEIGTPPQTL YLQLDTGSSD MIVNNADIAY 101 CKSMSDGSDY ASTDNYELTA TFNGLPSTTI SSEAYNTLCS YWGTFDASNS 151 STFENNATFF NNTYGDGTYY AGTYGTDVVS FENITLNDFT FGVSNDTIGN 201 PSGILGISLP IAEFTDGIEY ALALNRTPFI YDNFPMELKN QGKINKIAYS 251 LFLNGPDAHF GSILFGAVDK SKYTGQLYTL PMLQAFNTLG SNPGMIITAQ 301 SVAILDSESG NKTVSDIQFP VMLDSGTTFS YLPTEIAEAI GKSFDGEYSS 351 DDQGYIFDCS KVNDTLLSVD FGGFNISANI SNFVTSAKDR CVLNVKQSES 401 TYMLGDAFLV DAYVVYDLEN YEISIAQASF NNQEEDIEVI SDTVPGATPA 451 PGYFSTWVYK PGSPIGTGDF INVSWTSYSE FSQYKSLLAT AAQSDDASSF 501 SSSGGSSEST TKKQNAGYKY RSSFSFSLLS FISYFLL*

Amino Acid Sequence (or in FASTA format)

       1  MQLISILSLL SSLMCSLTVL GSSASSYVKF PVQKLADIIN ICTQDVSTVF
      51  KRNEVLNTTV INGIGVYVVK MEIGTPPQTL YLQLDTGSSD MIVNNADIAY
     101  CKSMSDGSDY ASTDNYELTA TFNGLPSTTI SSEAYNTLCS YWGTFDASNS
     151  STFENNATFF NNTYGDGTYY AGTYGTDVVS FENITLNDFT FGVSNDTIGN
     201  PSGILGISLP IAEFTDGIEY ALALNRTPFI YDNFPMELKN QGKINKIAYS
     251  LFLNGPDAHF GSILFGAVDK SKYTGQLYTL PMLQAFNTLG SNPGMIITAQ
     301  SVAILDSESG NKTVSDIQFP VMLDSGTTFS YLPTEIAEAI GKSFDGEYSS
     351  DDQGYIFDCS KVNDTLLSVD FGGFNISANI SNFVTSAKDR CVLNVKQSES
     401  TYMLGDAFLV DAYVVYDLEN YEISIAQASF NNQEEDIEVI SDTVPGATPA
     451  PGYFSTWVYK PGSPIGTGDF INVSWTSYSE FSQYKSLLAT AAQSDDASSF
     501  SSSGGSSEST TKKQNAGYKY RSSFSFSLLS FISYFLL*

external links for Yps6p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Yps6p

1)	Olsen V, et al. (1999) Identification and characterization of Saccharomyces cerevisiae yapsin 3, a new member of the yapsin family of aspartic proteases encoded by the YPS3 gene. Biochem J 339 ( Pt 2)():407-11
2)	Krysan DJ, et al. (2005) Yapsins are a family of aspartyl proteases required for cell wall integrity in Saccharomyces cerevisiae. Eukaryot Cell 4(8):1364-74