HXT12/YIL170W Protein Information

Standard Name	Hxt12p
Systematic Name	Yil170wp
Description	Possible pseudogene in strain S288C; YIL170W/HXT12 and the adjacent ORF, YIL171W, together encode a non-functional member of the hexose transporter family (1, 2, 3, 4)
Name Description	HeXose Transporter

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	457
Molecular Weight (Da)	50,830
Isoelectric Point (pI)	8.48

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Post-translational Modifications	PhosphoGRID
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Hxt12p (InterPro)
Transmembrane Domains	There are 10 total predicted transmembrane domains (TMHMM)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 1 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013B46B \| P40441 NCBI: 600807 \| 731897 GenBank/EMBL/DDBJ: Z46881
External Classifications	TC: 2.A.1.1 [The Sugar Porter (SP) Family]

Amino Acid Sequence (or in FASTA format)
1 MGLIVSIFNI GCAIGGIVLS KVGDIYGRRI GLITVTAIYV VGILIQITSI 51 NKWYQYFIGR IISGIGVGGI AVLSPMLISE VAPKHIRGTL VQLYQLMGTM 101 GIFLGYCTNY GTKNYHNATQ WRVGLGLCFA WATFMVSGMM FVPESPRYLI 151 EVGKDEEAKH SLSKSNKVSV DDPALLAEYD TIKAGIEIEK LAGNASWSEL 201 LSTKTKVFQR VLMGVIIQSL QQLTGDNYFF YYGTTIFKSV GLKDSFQTSI 251 IIGVVNFFSS FIAVYTIERF GRRTCLLWGA ASMLCCFAVF ASVGVTKLWP 301 QGSSHQDITS QGAGNCMIVF TMFFIFSFAT TWAGGCFVIV SETFPLRAKS 351 RGMAIATAAN WMWGFLISFF TPFITGAINF YYGYVFLGCL VFAYFYVFFF 401 VPETKGLTLE EVNTMWLEGV PAWKSASWVP PERRTADYDA DAIDHDNRPI 451 YKRFFSS*

Amino Acid Sequence (or in FASTA format)

       1  MGLIVSIFNI GCAIGGIVLS KVGDIYGRRI GLITVTAIYV VGILIQITSI
      51  NKWYQYFIGR IISGIGVGGI AVLSPMLISE VAPKHIRGTL VQLYQLMGTM
     101  GIFLGYCTNY GTKNYHNATQ WRVGLGLCFA WATFMVSGMM FVPESPRYLI
     151  EVGKDEEAKH SLSKSNKVSV DDPALLAEYD TIKAGIEIEK LAGNASWSEL
     201  LSTKTKVFQR VLMGVIIQSL QQLTGDNYFF YYGTTIFKSV GLKDSFQTSI
     251  IIGVVNFFSS FIAVYTIERF GRRTCLLWGA ASMLCCFAVF ASVGVTKLWP
     301  QGSSHQDITS QGAGNCMIVF TMFFIFSFAT TWAGGCFVIV SETFPLRAKS
     351  RGMAIATAAN WMWGFLISFF TPFITGAINF YYGYVFLGCL VFAYFYVFFF
     401  VPETKGLTLE EVNTMWLEGV PAWKSASWVP PERRTADYDA DAIDHDNRPI
     451  YKRFFSS*

external links for Hxt12p

Homologs	Interaction Resources	Protein databases/Other
BioGRID	SCOP Superfamily	Organelle DB
DIP	Pfam domains	YeastGFP
	TCDB
	YeastRC Structure Prediction (Seattle)

References cited on this page View Complete Literature Guide for Hxt12p

1)	Wieczorke R, et al. (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8
2)	Nelissen B, et al. (1995) Phylogenetic classification of the major superfamily of membrane transport facilitators, as deduced from yeast genome sequencing. FEBS Lett 377(2):232-6
3)	Andre B (1995) An overview of membrane transport proteins in Saccharomyces cerevisiae. Yeast 11(16):1575-611
4)	Kruckeberg AL (1996) The hexose transporter family of Saccharomyces cerevisiae. Arch Microbiol 166(5):283-92