RHO3/YIL118W Protein Information

Standard Name	Rho3p
Systematic Name	Yil118wp
ORF Classification	Verified
Description	Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p (1, 2)
Name Description	Ras HOmolog 3

Experimental Data
Molecules/cell	5910 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	231
Molecular Weight (Da)	25,312
Isoelectric Point (pI)	4.73

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Rho3p (InterPro)
Physical Interactions	There are 34 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013388B \| Q00245 MIPS: YIL118W NCBI: 218474 \| 45269605 \| 599999 \| 6322073 \| 730509 \| NP_012148.1 GenBank/EMBL/DDBJ: DAA08435.1 \| AY557857 \| D10006 \| Z46833

Amino Acid Sequence (or in FASTA format)
1 MSFLCGSAST SNKPIERKIV ILGDGACGKT SLLNVFTRGY FPEVYEPTVF 51 ENYIHDIFVD SKHITLSLWD TAGQEEFDRL RSLSYSDTQC IMLCFSIDSR 101 DSLENVQNKW VGEITDHCEG VKLVLVALKC DLRNNENESN AITPNNIQQD 151 NSVSNDNGNN INSTSNGKNL ISYEEGLAMA KKIGALRYLE CSAKLNKGVN 201 EAFTEAARVA LTAGPVATEV KSDSGSSCTI M*

Amino Acid Sequence (or in FASTA format)

       1  MSFLCGSAST SNKPIERKIV ILGDGACGKT SLLNVFTRGY FPEVYEPTVF
      51  ENYIHDIFVD SKHITLSLWD TAGQEEFDRL RSLSYSDTQC IMLCFSIDSR
     101  DSLENVQNKW VGEITDHCEG VKLVLVALKC DLRNNENESN AITPNNIQQD
     151  NSVSNDNGNN INSTSNGKNL ISYEEGLAMA KKIGALRYLE CSAKLNKGVN
     201  EAFTEAARVA LTAGPVATEV KSDSGSSCTI M*

external links for Rho3p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Candida (CGD)	BioPIXIE	MIPS	YeastGFP
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA
	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Rho3p

1)	Doignon F, et al. (1999) The yeast Rgd1p is a GTPase activating protein of the Rho3 and rho4 proteins. FEBS Lett 459(3):458-62
2)	Madden K and Snyder M (1998) Cell polarity and morphogenesis in budding yeast. Annu Rev Microbiol 52():687-744
3)	Matsui Y and Toh-e A (1992) Isolation and characterization of two novel ras superfamily genes in Saccharomyces cerevisiae. Gene 114(1):43-9
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41