SEC24/YIL109C Protein Information Help

Standard Name Sec24p
Systematic Name Yil109cp
Alias Anu1p
ORF Classification Verified
Description Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat; required for cargo selection during vesicle formation in ER to Golgi transport; homologous to Sfb3p; SEC24 has a paralog, SFB2, that arose from the whole genome duplication (1, 2, 3)
Name Description SECretory
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 926
Molecular Weight (Da) 103,635
Isoelectric Point (pI) 6.16

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Sec24p (InterPro)
Physical Interactions There are 86 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000112562 | P40482
MIPS: YIL109C
NCBI: 24158938 | 34810534 | 34810536 | 34810538 | 398364269 | 51013227 | 558697 | 731857 | NP_012157.3
GenBank/EMBL/DDBJ: DAA08444.1 | AY692888 | Z38125
Amino Acid Sequence (or in FASTA format)
 
       1  MSHHKKRVYP QAQLQYGQNA TPLQQPAQFM PPQDPAAAGM SYGQMGMPPQ
      51  GAVPSMGQQQ FLTPAQEQLH QQIDQATTSM NDMHLHNVPL VDPNAYMQPQ
     101  VPVQMGTPLQ QQQQPMAAPA YGQPSAAMGQ NMRPMNQLYP IDLLTELPPP
     151  ITDLTLPPPP LVIPPERMLV PSELSNASPD YIRSTLNAVP KNSSLLKKSK
     201  LPFGLVIRPY QHLYDDIDPP PLNEDGLIVR CRRCRSYMNP FVTFIEQGRR
     251  WRCNFCRLAN DVPMQMDQSD PNDPKSRYDR NEIKCAVMEY MAPKEYTLRQ
     301  PPPATYCFLI DVSQSSIKSG LLATTINTLL QNLDSIPNHD ERTRISILCV
     351  DNAIHYFKIP LDSENNEESA DQINMMDIAD LEEPFLPRPN SMVVSLKACR
     401  QNIETLLTKI PQIFQSNLIT NFALGPALKS AYHLIGGVGG KIIVVSGTLP
     451  NLGIGKLQRR NESGVVNTSK ETAQLLSCQD SFYKNFTIDC SKVQITVDLF
     501  LASEDYMDVA SLSNLSRFTA GQTHFYPGFS GKNPNDIVKF STEFAKHISM
     551  DFCMETVMRA RGSTGLRMSR FYGHFFNRSS DLCAFSTMPR DQSYLFEVNV
     601  DESIMADYCY VQVAVLLSLN NSQRRIRIIT LAMPTTESLA EVYASADQLA
     651  IASFYNSKAV EKALNSSLDD ARVLINKSVQ DILATYKKEI VVSNTAGGAP
     701  LRLCANLRMF PLLMHSLTKH MAFRSGIVPS DHRASALNNL ESLPLKYLIK
     751  NIYPDVYSLH DMADEAGLPV QTEDGEATGT IVLPQPINAT SSLFERYGLY
     801  LIDNGNELFL WMGGDAVPAL VFDVFGTQDI FDIPIGKQEI PVVENSEFNQ
     851  RVRNIINQLR NHDDVITYQS LYIVRGASLS EPVNHASARE VATLRLWASS
     901  TLVEDKILNN ESYREFLQIM KARISK*

external links for Sec24p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Candida (CGD) BioPIXIE MIPS YeastGFP
Candida (CandidaDB) CYC2008 (complexes) Pfam domains YeastRC Public Image Repository
YGOB Complexome YeastRC Structure Prediction (Seattle)
YOGY DIP


GeneMANIA

References cited on this page View Complete Literature Guide for Sec24p
1) Miller EA, et al.  (2003) Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles. Cell 114(4):497-509
2) Duden R  (2003) ER-to-Golgi transport: COP I and COP II function (Review). Mol Membr Biol 20(3):197-207
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61