UTP25/YIL091C Protein Information Help

Standard Name Utp25p 1
Systematic Name Yil091cp
ORF Classification Verified
Description Nucleolar protein required for 35S pre-RNA processing and 40S ribosomal subunit biogenesis (1, 2, 3, 4)
Name Description U Three Protein 1
Experimental Data
Molecules/cell 172 5
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 721
Molecular Weight (Da) 83,991
Isoelectric Point (pI) 6.28

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Utp25p (InterPro)
Physical Interactions There are 29 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000013B420 | P40498
MIPS: YIL091C
NCBI: 577123 | 6322100 | 731842 | NP_012175.1
GenBank/EMBL/DDBJ: DAA08462.1 | Z46728
Amino Acid Sequence (or in FASTA format)
 
       1  MSDSSVREKN DNFRGYRKRG RQELRKIKRS SARTEGGSTE TLEDVAEDID
      51  HRSDEDEVSD VDSGDDFDIE DEEGKKEKVY DALLTILKSE HPEPKRRRRE
     101  ADESNKAPAE VGEDEHENTE HGPVDDQLEI ENGLLGNHED DNDDDSSGDE
     151  KDIDSEDEQD PFESHFNQVP EKFVDKLSNA FKTKSVKYKS VKGSLSDSES
     201  YIYAKPVVIG EEALVESPYR SSSIYSYFLK QRLKVQNGLL DKKTDPLTAL
     251  QKKLVDPMFQ YKDILYEYDS YEKDEDEYRD LYALHVLNHI YKTRDRILKN
     301  NQRLQDNPDT EHLDQGFTRP KVLIVVPTRE VAYRVVDKII SKSGIDQVDK
     351  KGKFYDQFRD DSLPPKSKPK SFQHIFRGNT NDFFVVGLKF TRKAIKLYSN
     401  FYQSDIIVCS PLGIQMILEN TDKKKRQDDF LSSIELMVID QLHSIEYQNI
     451  SHIFTIFDHL NKIPDQQHEA DFSRIRMWYI NEQAKLFRQT MVFTKYISPA
     501  ANSLINGRCR NMAGRWKNHK VIGSENSSIG QSGLKIRQIF QRFDIIGNSI
     551  IEEPDYRFKF FTSVIIPGIV KSTGYEDGIL IYIPDYTDFI RIRNYMKEKT
     601  TILFGDINEY SSQRQLNANR SLFQQGRLKV MLYTERLHHY RRYEIKGVKS
     651  VVFYKPPNNP EFYNEVVRFI GKNAFLGNTD LNISTVRCIY SKLDGLSLER
     701  IVGTKRAAVL SHAQKEIYEF K*

external links for Utp25p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Candida (CGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CandidaDB) CYC2008 (complexes) Pfam domains
YGOB Complexome YeastRC Structure Prediction (Seattle)
YOGY DIP


GeneMANIA


YeastRC Mass Spec (Seattle)


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Utp25p
1) Charette JM and Baserga SJ  (2010) The DEAD-box RNA helicase-like Utp25 is an SSU processome component. RNA 16(11):2156-69
2) Hazbun TR, et al.  (2003) Assigning function to yeast proteins by integration of technologies. Mol Cell 12(6):1353-65
3) Li Z, et al.  (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213
4) Goldfeder MB and Oliveira CC  (2010) Utp25p, a nucleolar Saccharomyces cerevisiae protein, interacts with U3 snoRNP subunits and affects processing of the 35S pre-rRNA. FEBS J 277(13):2838-52
5) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41