KTR7/YIL085C Protein Information

Standard Name	Ktr7p
Systematic Name	Yil085cp
ORF Classification	Verified
Description	Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family; KTR7 has a paralog, KTR5, that arose from the whole genome duplication (1, 2)
Name Description	Kre Two Related 1

Experimental Data
Molecules/cell	2890 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	517
Molecular Weight (Da)	61,437
Isoelectric Point (pI)	5.06

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Ktr7p (InterPro)
Transmembrane Domains	There are 1 total predicted transmembrane domains (TMHMM)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 1 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000012E120 \| P40504 MIPS: YIL085C NCBI: 398364323 \| 577129 \| 731836 \| NP_012181.3 GenBank/EMBL/DDBJ: DAA08467.1 \| Z46728
External Classifications	EC: 2.4.1.- [Hexosyltransferases] EC: 2.4.1.131 [GDP-Man:Man(3)GlcNAc(2)-PP-dolichol alpha-1,2-mannosyltransferase]

Amino Acid Sequence (or in FASTA format)
1 MAIRLNPKVR RFLLDKCRQK RYGFLFLGCI FAILYCMGTW PFFAKDIVHD 51 PNNLPYSLQD YSTDKDEPFF RGCTDTKLYL QNPAYSKMNA SFVMLTRNEE 101 IEDVLKTMRS IEGHFNKWFK YPYVFLNDDP FTDHFKDQIQ AATNATVEFG 151 TVDEIMWEFP AKVRNSLQFK ASLEDQNDRG IMYGNMESYH KMCRFYSGIF 201 YKHPLVSKYE WYWRIEPDVD FFCDISYDPF FEMAKHNKKY GFTVLITELY 251 WTVPNLFRTT KSFIKKTAGL KENLGTLWKL FTFNYNILDT DDEEISRWVN 301 FPWDAKPKLT EKLMVDFLLE NHGQVNNEED LEGIQYLVER ARSKVPMLED 351 SLEGEDYNLC HFWSNFEIAR VDLFDNEIYN AYFKFLEESG GFWTERWGDA 401 PIHSIGLGMT LDLEDVHYFR DIGYRHSSLQ HCPKNALQSQ ENLNTFDEGY 451 NFGCGCRCVC PKKGEDIEDH STPCMDIFFE LLHGREYEKE FPGCYKPSIK 501 DKDVIEEIRR ENFRVIE*

Amino Acid Sequence (or in FASTA format)

       1  MAIRLNPKVR RFLLDKCRQK RYGFLFLGCI FAILYCMGTW PFFAKDIVHD
      51  PNNLPYSLQD YSTDKDEPFF RGCTDTKLYL QNPAYSKMNA SFVMLTRNEE
     101  IEDVLKTMRS IEGHFNKWFK YPYVFLNDDP FTDHFKDQIQ AATNATVEFG
     151  TVDEIMWEFP AKVRNSLQFK ASLEDQNDRG IMYGNMESYH KMCRFYSGIF
     201  YKHPLVSKYE WYWRIEPDVD FFCDISYDPF FEMAKHNKKY GFTVLITELY
     251  WTVPNLFRTT KSFIKKTAGL KENLGTLWKL FTFNYNILDT DDEEISRWVN
     301  FPWDAKPKLT EKLMVDFLLE NHGQVNNEED LEGIQYLVER ARSKVPMLED
     351  SLEGEDYNLC HFWSNFEIAR VDLFDNEIYN AYFKFLEESG GFWTERWGDA
     401  PIHSIGLGMT LDLEDVHYFR DIGYRHSSLQ HCPKNALQSQ ENLNTFDEGY
     451  NFGCGCRCVC PKKGEDIEDH STPCMDIFFE LLHGREYEKE FPGCYKPSIK
     501  DKDVIEEIRR ENFRVIE*

external links for Ktr7p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Ktr7p

1)	Lussier M, et al. (1997) Completion of the Saccharomyces cerevisiae genome sequence allows identification of KTR5, KTR6 and KTR7 and definition of the nine-membered KRE2/MNT1 mannosyltransferase gene family in this organism. Yeast 13(3):267-74
2)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41