BCY1/YIL033C Protein Information Help

Standard Name Bcy1p 1
Systematic Name Yil033cp
Alias Sra1p 2
ORF Classification Verified
Description Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA); PKA is a component of a signaling pathway that controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation (3, 4)
Name Description Bypass of CYclic-AMP requirement 1
Experimental Data
Molecules/cell 4280 5
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 416
Molecular Weight (Da) 47,219
Isoelectric Point (pI) 8.14

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Bcy1p (InterPro)
Physical Interactions There are 74 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000052E93 | P07278
MIPS: YIL033C
NCBI: 125222 | 171159 | 172689 | 313103903 | 4303 | 45270064 | 600015 | 6322156 | NP_012231.1 | NM_001179383.1
GenBank/EMBL/DDBJ: AAA34468.1 | AAA66934.1 | AAS56413.1 | CAA28726.1 | CAA86918.1 | DAA08515.1 | AY558087 | M15756 | M17223 | X05051 | Z46861
Amino Acid Sequence (or in FASTA format)
       1  MVSSLPKESQ AELQLFQNEI NAANPSDFLQ FSANYFNKRL EQQRAFLKAR
      51  EPEFKAKNIV LFPEPEESFS RPQSAQSQSR SRSSVMFKSP FVNEDPHSNV
     101  FKSGFNLDPH EQDTHQQAQE EQQHTREKTS TPPLPMHFNA QRRTSVSGET
     151  LQPNNFDDWT PDHYKEKSEQ QLQRLEKSIR NNFLFNKLDS DSKRLVINCL
     201  EEKSVPKGAT IIKQGDQGDY FYVVEKGTVD FYVNDNKVNS SGPGSSFGEL
     251  ALMYNSPRAA TVVATSDCLL WALDRLTFRK ILLGSSFKKR LMYDDLLKSM
     301  PVLKSLTTYD RAKLADALDT KIYQPGETII REGDQGENFY LIEYGAVDVS
     351  KKGQGVINKL KDHDYFGEVA LLNDLPRQAT VTATKRTKVA TLGKSGFQRL
     401  LGPAVDVLKL NDPTRH*                                    

external links for Bcy1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Aspergillus (AspGD) CYC2008 (complexes) MIPS YeastGFP
Candida (CGD) Complexome Pfam domains YeastRC Public Image Repository
YGOB DIP YeastRC Structure Prediction (Seattle)
YOGY GeneMANIA


IMP


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Bcy1p
1) Matsumoto K, et al.  (1982) Isolation and characterization of yeast mutants deficient in adenylate cyclase and cAMP-dependent protein kinase. Proc Natl Acad Sci U S A 79(7):2355-9
2) Cannon JF and Tatchell K  (1987) Characterization of Saccharomyces cerevisiae genes encoding subunits of cyclic AMP-dependent protein kinase. Mol Cell Biol 7(8):2653-63
3) Toda T, et al.  (1987) Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae. Mol Cell Biol 7(4):1371-7
4) Cannon JF, et al.  (1990) Yeast cAMP-dependent protein kinase regulatory subunit mutations display a variety of phenotypes. J Biol Chem 265(20):11897-904
5) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41