MNT3/YIL014W Protein Information

Standard Name	Mnt3p
Systematic Name	Yil014wp
ORF Classification	Verified
Description	Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-linked glycans during protein O-glycosylation (1)
Name Description	MaNnosylTransferase

Experimental Data
Molecules/cell	2310 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	630
Molecular Weight (Da)	72,409
Isoelectric Point (pI)	5.36

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Mnt3p (InterPro)
Transmembrane Domains	There are 1 total predicted transmembrane domains (TMHMM)
Signal Peptide(s)	There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions	There are 5 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000012F2AB \| P40549 MIPS: YIL014W NCBI: 398364497 \| 45270104 \| 599986 \| 731782 \| NP_012251.3 GenBank/EMBL/DDBJ: DAA08532.1 \| AY558107 \| Z46881
External Classifications	EC: 2.4.1.- [Hexosyltransferases]

Amino Acid Sequence (or in FASTA format)
1 MLKSLKSRRL ILKRLVTLLL SLFFSYLIFS ASRNVTSSNK LNNHASERTA 51 VESSAFNWIE KRQHQVRSEN LMNRLSAYFL PFLSRSSHKE RVLLRQLGNN 101 EIAKSDKCRY IFEVLYKIDP DWDNAQTAKF YNVDGVDNTL ASLLGERLRS 151 YDYCFLSGQL DPTAIFANST VNPHDLQNRM FPFLKKINEE SKTVMWPIIT 201 DMTTGEAVPA PEVDMESSNF NGNFWSNWNR LSKGRGFVLT IAEKDVPLFL 251 KQLKVMEFSK NELPFQIVST GNELSAESIA KISETAKETE QRVYLVDCST 301 VLDTNFANTY ISFFQNKWVA TLFNTFEEYI LLDADVVPFV GSDYFFDSPS 351 YRESGILLFK DRVMENEQTF QYCIEMLNEV EPSAQERRFI GSRLVFDSSL 401 PFSSETSEEA SVYYNFFKKL RLHHVDSGLV VVNKLEKLNG LLMSFMLNLD 451 GKLQRCVYGD KEIFWLGQLY AGQDYSINPV DGSIIGPVNE EPENDDGHKS 501 GMYYICSTQI AHSDSKNRLL WVNGGLKTCK ISNSAEDDFG REPEYFKSRY 551 GDISKLKRIY DASLNVEGLI VPDVSVHPWM QIKECSNYMY CAYATGDGHT 601 NSELDEGRLI TFTEKELRYI NDISRTWNAN *

Amino Acid Sequence (or in FASTA format)

       1  MLKSLKSRRL ILKRLVTLLL SLFFSYLIFS ASRNVTSSNK LNNHASERTA
      51  VESSAFNWIE KRQHQVRSEN LMNRLSAYFL PFLSRSSHKE RVLLRQLGNN
     101  EIAKSDKCRY IFEVLYKIDP DWDNAQTAKF YNVDGVDNTL ASLLGERLRS
     151  YDYCFLSGQL DPTAIFANST VNPHDLQNRM FPFLKKINEE SKTVMWPIIT
     201  DMTTGEAVPA PEVDMESSNF NGNFWSNWNR LSKGRGFVLT IAEKDVPLFL
     251  KQLKVMEFSK NELPFQIVST GNELSAESIA KISETAKETE QRVYLVDCST
     301  VLDTNFANTY ISFFQNKWVA TLFNTFEEYI LLDADVVPFV GSDYFFDSPS
     351  YRESGILLFK DRVMENEQTF QYCIEMLNEV EPSAQERRFI GSRLVFDSSL
     401  PFSSETSEEA SVYYNFFKKL RLHHVDSGLV VVNKLEKLNG LLMSFMLNLD
     451  GKLQRCVYGD KEIFWLGQLY AGQDYSINPV DGSIIGPVNE EPENDDGHKS
     501  GMYYICSTQI AHSDSKNRLL WVNGGLKTCK ISNSAEDDFG REPEYFKSRY
     551  GDISKLKRIY DASLNVEGLI VPDVSVHPWM QIKECSNYMY CAYATGDGHT
     601  NSELDEGRLI TFTEKELRYI NDISRTWNAN *

external links for Mnt3p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Mnt3p

1)	Romero PA, et al. (1999) Mnt2p and Mnt3p of Saccharomyces cerevisiae are members of the Mnn1p family of alpha-1,3-mannosyltransferases responsible for adding the terminal mannose residues of O-linked oligosaccharides. Glycobiology 9(10):1045-51
2)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41