TIR3/YIL011W Protein Information Help

Standard Name Tir3p 1
Systematic Name Yil011wp
Alias Yib1p
ORF Classification Verified
Description Cell wall mannoprotein; member of Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth; TIR3 has a paralog, TIR2, that arose from the whole genome duplication (1, 2, 3)
Name Description TIp1-Related 1
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 269
Molecular Weight (Da) 26,308
Isoelectric Point (pI) 3.99

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Tir3p (InterPro)
Signal Peptide(s) There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions There are 2 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000136FB9 | P40552
MIPS: YIL011W
NCBI: 558391 | 6322179 | 731779 | NP_012254.1 | NM_001179361.1
GenBank/EMBL/DDBJ: CAA86238.1 | DAA08534.1 | Z38113
Amino Acid Sequence (or in FASTA format)
       1  MSFTKIAALL AVAAASTQLV SAEVGQYEIV EFDAILADVK ANLEQYMSLA
      51  MNNPDFTLPS GVLDVYQHMT TATDDSYTSY FTEMDFAQIT TAMVQVPWYS
     101  SRLEPEIIAA LQSAGISITS LGQTVSESGS ESATASSDAS SASESSSAAS
     151  SSASESSSAA SSSASESSSA ASSSASESSS AASSSASEAA KSSSSAKSSG
     201  SSAASSAASS ASSKASSAAS SSAKASSSAE KSTNSSSSAT SKNAGAAMDM
     251  GFFSAGVGAA IAGAAAMLL*                                 

external links for Tir3p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
YGOB CYC2008 (complexes) MIPS
YOGY Complexome Pfam domains

DIP YeastRC Structure Prediction (Seattle)

GeneMANIA


IMP

References cited on this page View Complete Literature Guide for Tir3p
1) Abramova NE, et al.  (2001) Reciprocal regulation of anaerobic and aerobic cell wall mannoprotein gene expression in Saccharomyces cerevisiae. J Bacteriol 183(9):2881-7
2) Hamada K, et al.  (1999) Amino acid residues in the omega-minus region participate in cellular localization of yeast glycosylphosphatidylinositol-attached proteins. J Bacteriol 181(13):3886-9
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61