DOT5/YIL010W Protein Information Help

Standard Name Dot5p 1
Systematic Name Yil010wp
ORF Classification Verified
Description Nuclear thiol peroxidase; functions as an alkyl-hydroperoxide reductase during post-diauxic growth (2)
Name Description Disruptor Of Telomeric silencing 1
Experimental Data
Molecules/cell 1840 3
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 215
Molecular Weight (Da) 24,119
Isoelectric Point (pI) 10.13

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Dot5p (InterPro)
Physical Interactions There are 10 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI00001296B5 | P40553
MIPS: YIL010W
NCBI: 398364507 | 45270486 | 558392 | 731778 | 93278640 | NP_012255.3 | NM_001179360.3
GenBank/EMBL/DDBJ: AAS56624.1 | CAA86239.1 | DAA08535.1 | AY558298 | Z38113
External Classifications EC: 1.11.1.15 [Peroxiredoxin]
Amino Acid Sequence (or in FASTA format)
       1  MGEALRRSTR IAISKRMLEE EESKLAPIST PEVPKKKIKT GPKHNANQAV
      51  VQEANRSSDV NELEIGDPIP DLSLLNEDND SISLKKITEN NRVVVFFVYP
     101  RASTPGCTRQ ACGFRDNYQE LKKYAAVFGL SADSVTSQKK FQSKQNLPYH
     151  LLSDPKREFI GLLGAKKTPL SGSIRSHFIF VDGKLKFKRV KISPEVSVND
     201  AKKEVLEVAE KFKEE*                                     

external links for Dot5p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily LoQate
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Candida (CGD) CYC2008 (complexes) MIPS YeastGFP
YGOB Complexome Pfam domains YeastRC Public Image Repository
YOGY DIP YeastRC Structure Prediction (Seattle)

GeneMANIA


IMP

References cited on this page View Complete Literature Guide for Dot5p
1) Singer MS, et al.  (1998) Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae. Genetics 150(2):613-32
2) Cha MK, et al.  (2003) Nuclear thiol peroxidase as a functional alkyl-hydroperoxide reductase necessary for stationary phase growth of Saccharomyces cerevisiae. J Biol Chem 278(27):24636-43
3) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41