CFD1/YIL003W Protein Information

Standard Name	Cfd1p 1
Systematic Name	Yil003wp
Alias	Dre3p 2
ORF Classification	Verified
Description	Highly conserved, iron-sulfur cluster binding protein localized in the cytoplasm; forms a complex with Nbp35p that is involved in iron-sulfur protein assembly in the cytosol (1, 3)
Name Description	Cytosolic Fe-S cluster Deficient 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	293
Molecular Weight (Da)	31,922
Isoelectric Point (pI)	5.33

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Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Cfd1p (InterPro)
Physical Interactions	There are 8 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013B35D \| P40558 MIPS: YIL003W NCBI: 45270484 \| 557847 \| 558401 \| 6322188 \| 731773 \| NP_012263.1 GenBank/EMBL/DDBJ: DAA08543.1 \| AY558297 \| X79743 \| Z38062 \| Z38113

Amino Acid Sequence (or in FASTA format)
1 MEEQEIGVPA ASLAGIKHII LILSGKGGVG KSSVTTQTAL TLCSMGFKVG 51 VLDIDLTGPS LPRMFGLENE SIYQGPEGWQ PVKVETNSTG SLSVISLGFL 101 LGDRGNSVIW RGPKKTSMIK QFISDVAWGE LDYLLIDTPP GTSDEHISIA 151 EELRYSKPDG GIVVTTPQSV ATADVKKEIN FCKKVDLKIL GIIENMSGFV 201 CPHCAECTNI FSSGGGKRLS EQFSVPYLGN VPIDPKFVEM IENQVSSKKT 251 LVEMYRESSL CPIFEEIMKK LRKQDTTTPV VDKHEQPQIE SPK*

Amino Acid Sequence (or in FASTA format)

       1  MEEQEIGVPA ASLAGIKHII LILSGKGGVG KSSVTTQTAL TLCSMGFKVG
      51  VLDIDLTGPS LPRMFGLENE SIYQGPEGWQ PVKVETNSTG SLSVISLGFL
     101  LGDRGNSVIW RGPKKTSMIK QFISDVAWGE LDYLLIDTPP GTSDEHISIA
     151  EELRYSKPDG GIVVTTPQSV ATADVKKEIN FCKKVDLKIL GIIENMSGFV
     201  CPHCAECTNI FSSGGGKRLS EQFSVPYLGN VPIDPKFVEM IENQVSSKKT
     251  LVEMYRESSL CPIFEEIMKK LRKQDTTTPV VDKHEQPQIE SPK*

external links for Cfd1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	GeneMANIA
YOGY	YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Cfd1p

1)	Roy A, et al. (2003) A novel eukaryotic factor for cytosolic Fe-S cluster assembly. EMBO J 22(18):4826-35
2)	Woolford, J (2001) personal communication
3)	Netz DJ, et al. (2007) The Cfd1-Nbp35 complex acts as a scaffold for iron-sulfur protein assembly in the yeast cytosol. Nat Chem Biol 3(5):278-86