EGD2/YHR193C Protein Information

Standard Name	Egd2p 1
Systematic Name	Yhr193cp
ORF Classification	Verified
Description	Alpha subunit of the heteromeric nascent polypeptide-associated complex (NAC) involved in protein sorting and translocation, associated with cytoplasmic ribosomes (1, 2, 3)
Name Description	Enhancer of Gal4 DNA binding 1

Experimental Data
Molecules/cell	38000 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	174
Molecular Weight (Da)	18,709
Isoelectric Point (pI)	4.67

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Egd2p (InterPro)
Physical Interactions	There are 57 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000129DEF \| P38879 MIPS: YHR193C NCBI: 172043 \| 398364983 \| 45270466 \| 458941 \| 595984 \| 731762 \| NP_012063.3 GenBank/EMBL/DDBJ: DAA06885.1 \| AY558288 \| L12222 \| U00030 \| U17134

Amino Acid Sequence (or in FASTA format)
1 MSAIPENANV TVLNKNEKKA RELIGKLGLK QIPGIIRVTF RKKDNQIYAI 51 EKPEVFRSAG GNYVVFGEAK VDNFTQKLAA AQQQAQASGI MPSNEDVATK 101 SPEDIQADMQ AAAEGSVNAA AEEDDEEGEV DAGDLNKDDI ELVVQQTNVS 151 KNQAIKALKA HNGDLVNAIM SLSK*

Amino Acid Sequence (or in FASTA format)

       1  MSAIPENANV TVLNKNEKKA RELIGKLGLK QIPGIIRVTF RKKDNQIYAI
      51  EKPEVFRSAG GNYVVFGEAK VDNFTQKLAA AQQQAQASGI MPSNEDVATK
     101  SPEDIQADMQ AAAEGSVNAA AEEDDEEGEV DAGDLNKDDI ELVVQQTNVS
     151  KNQAIKALKA HNGDLVNAIM SLSK*

external links for Egd2p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastGFP
Candida (CGD)	CYC2008 (complexes)	Pfam domains	YeastRC Public Image Repository
Candida (CandidaDB)	Complexome	YeastRC Structure Prediction (Seattle)
YGOB	DIP
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Egd2p

1)	Shi X, et al. (1995) The yeast EGD2 gene encodes a homologue of the alpha NAC subunit of the human nascent-polypeptide-associated complex. Gene 165(2):199-202
2)	George R, et al. (1998) The yeast nascent polypeptide-associated complex initiates protein targeting to mitochondria in vivo. Proc Natl Acad Sci U S A 95(5):2296-301
3)	Reimann B, et al. (1999) Initial characterization of the nascent polypeptide-associated complex in yeast. Yeast 15(5):397-407
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41