YHR182W Protein Information

Systematic Name	Yhr182wp
ORF Classification	Verified
Description	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and cytoplasm; relocalizes from bud neck to cytoplasm upon DNA replication stress (1, 2)

Experimental Data
Molecules/cell	1720 3

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	785
Molecular Weight (Da)	90,108
Isoelectric Point (pI)	6.32

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Yhr182wp (InterPro)
Physical Interactions	There are 13 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013B2F1 \| P38870 MIPS: YHR182W NCBI: 458911 \| 6321976 \| 731753 \| NP_012052.1 GenBank/EMBL/DDBJ: DAA06874.1 \| U00028

Amino Acid Sequence (or in FASTA format)
1 MSVKEHNEED IIGDELQNSR QLSIDCDSVK ISLRNTYWTK DYTTGIKLFI 51 KHMKRENDLL IKDIKFYNDF VNKFWKPTLN NLQKMEATNS MNSRLLEVMS 101 KQFNIISTEQ VERDCKIPLQ ELRDLNESFL REAENDLSSR YSAYIKDLVA 151 AKEALIGCEK RVQSIYKLKK ANTPVENSSS VFDNGKDSAP LTRLNFVCEF 201 PYTLDERLKF EDCDQFMSFL QTLKGKVILE KSVFSVPGLS NQSFQGRSLI 251 KELKKLEPRL NLSLFNIDRI GNEFIQLGII QEYSLSFYSS KVSQFDQEKY 301 YYWNSEVLAT QESNGNAGNR KKKSYGELTH SDNEHEEKSN VSSIKTSISD 351 WIRKVSQHDN DDCDAAGSTD MNKNEWKSLK QQLESSQDIF FSKCCQLEYS 401 KVQLEKTIYD YCKNYSKMED GIKRALESSN MMFQQKCEKF TDSPVCSLQE 451 AQLPQETANA DVRGFFLRDN GIPFRRWNIL EASDPVDACK EISIKSEKFF 501 CGSEINNELA ALDTLGAIKI ILRQIEKEPN ANKVIQSWHR DIDFVRVSNL 551 KRDLLGEFKG SKTTENTNSI ITAHFFENSH SYVTNDLVGL IKLWLLELPD 601 SLIPSNHYDD LIKAEKSLTS LCEQFPTSSL RFLQELANHF QLINSKYSLP 651 PQTIQDLFRD NSDIDIPLAH HFVRRTGLQN PIDIKILSPT LSTFFINERT 701 VETLQTLIAN RITTATTATL TEPPTIIIKD TTAPIHSTPK PPPNDKDGHF 751 IPRPFKTSST PTTPERPKRK SGLFLPINVN DVPST*

Amino Acid Sequence (or in FASTA format)

       1  MSVKEHNEED IIGDELQNSR QLSIDCDSVK ISLRNTYWTK DYTTGIKLFI
      51  KHMKRENDLL IKDIKFYNDF VNKFWKPTLN NLQKMEATNS MNSRLLEVMS
     101  KQFNIISTEQ VERDCKIPLQ ELRDLNESFL REAENDLSSR YSAYIKDLVA
     151  AKEALIGCEK RVQSIYKLKK ANTPVENSSS VFDNGKDSAP LTRLNFVCEF
     201  PYTLDERLKF EDCDQFMSFL QTLKGKVILE KSVFSVPGLS NQSFQGRSLI
     251  KELKKLEPRL NLSLFNIDRI GNEFIQLGII QEYSLSFYSS KVSQFDQEKY
     301  YYWNSEVLAT QESNGNAGNR KKKSYGELTH SDNEHEEKSN VSSIKTSISD
     351  WIRKVSQHDN DDCDAAGSTD MNKNEWKSLK QQLESSQDIF FSKCCQLEYS
     401  KVQLEKTIYD YCKNYSKMED GIKRALESSN MMFQQKCEKF TDSPVCSLQE
     451  AQLPQETANA DVRGFFLRDN GIPFRRWNIL EASDPVDACK EISIKSEKFF
     501  CGSEINNELA ALDTLGAIKI ILRQIEKEPN ANKVIQSWHR DIDFVRVSNL
     551  KRDLLGEFKG SKTTENTNSI ITAHFFENSH SYVTNDLVGL IKLWLLELPD
     601  SLIPSNHYDD LIKAEKSLTS LCEQFPTSSL RFLQELANHF QLINSKYSLP
     651  PQTIQDLFRD NSDIDIPLAH HFVRRTGLQN PIDIKILSPT LSTFFINERT
     701  VETLQTLIAN RITTATTATL TEPPTIIIKD TTAPIHSTPK PPPNDKDGHF
     751  IPRPFKTSST PTTPERPKRK SGLFLPINVN DVPST*

external links for Yhr182wp

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS	YeastRC Public Image Repository
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Yhr182wp

1)	Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
2)	Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76
3)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41