ARP1/YHR129C Protein Information Help

Standard Name Arp1p 1
Systematic Name Yhr129cp
Alias Act5p 2
ORF Classification Verified
Description Actin-related protein of the dynactin complex; required for spindle orientation and nuclear migration; forms actin-like short filament composed of 9 or 10 Arp1p monomers; putative ortholog of mammalian centractin (2, 3, 4)
Name Description Actin-Related Protein
Experimental Data
Molecules/cell 1580 5
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 384
Molecular Weight (Da) 42,995
Isoelectric Point (pI) 5.26

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Arp1p (InterPro)
Physical Interactions There are 31 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI0000126051 | P38696
MIPS: YHR129C
NCBI: 500679 | 51013619 | 557670 | 6321921 | 728795 | NP_011997.1 | NM_001179259.1
GenBank/EMBL/DDBJ: AAB68412.1 | AAT93103.1 | CAA56206.1 | DAA06822.1 | AY693084 | U10398 | X79811
Amino Acid Sequence (or in FASTA format)
       1  MDQLSDSYAL YNQPVVIDNG SGIIKAGFSG EERPKALEYC LVGNTKYDKV
      51  MLEGLQGDTF IGNNAQKLRG LLKLRYPIKH GVVEDWDSME LIWSYVLNEV
     101  LQLQNIGEHP LLITEAPMNP LKNREQMAQV LFETFDVSAL YVSNPAVLSL
     151  YASGRTTGCV VDCGEGYCST VPIYDGFALP ASMMRMDIGG ADITEQLQFQ
     201  LRKSAGVSLF SSSEREIVRT MKEKVCYLAK NIKKEEEKYL QGTQDLISTF
     251  KLPDGRCIEV GNDRYRAPEI LFSPQIIGLG YDGLSDMCMQ SIWKVDLDLR
     301  KPLLSSIILS GGTTTLKGFG DRMLWDLEAL TKGTSKIKII APSERKYTTW
     351  IGGSILTGLS TFQRLWTKKS DWLEDSTRVY SNLM*                

external links for Arp1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily LoQate
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Candida (CGD) CYC2008 (complexes) MIPS YeastGFP
YGOB Complexome Pfam domains YeastRC Public Image Repository
YOGY DIP YeastRC Structure Prediction (Seattle)

GeneMANIA


IMP


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Arp1p
1) Poch O and Winsor B  (1997) Who's who among the Saccharomyces cerevisiae actin-related proteins? A classification and nomenclature proposal for a large family. Yeast 13(11):1053-8
2) Muhua L, et al.  (1994) A yeast actin-related protein homologous to that in vertebrate dynactin complex is important for spindle orientation and nuclear migration. Cell 78(4):669-79
3) Clark SW and Meyer DI  (1994) ACT3: a putative centractin homologue in S. cerevisiae is required for proper orientation of the mitotic spindle. J Cell Biol 127(1):129-38
4) Igarashi R, et al.  (2005) Molecular dissection of ARP1 regions required for nuclear migration and cell wall integrity checkpoint functions in Saccharomyces cerevisiae. Cell Struct Funct 30(2):57-67
5) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41