RRP3/YHR065C Protein Information

Standard Name	Rrp3p 1
Systematic Name	Yhr065cp
ORF Classification	Verified
Description	Protein involved in rRNA processing; required for maturation of the 35S primary transcript of pre-rRNA and for cleavage leading to mature 18S rRNA; homologous to eIF-4a, which is a DEAD box RNA-dependent ATPase with helicase activity (1)
Name Description	Ribosomal RNA Processing 1

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	501
Molecular Weight (Da)	55,968
Isoelectric Point (pI)	9.91

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Rrp3p (InterPro)
Physical Interactions	There are 9 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI00001D4788 \| P38712 MIPS: YHR065C NCBI: 37362659 \| 37675480 \| 37675481 \| 487961 \| 81175193 \| NP_011932.2 \| NM_001179195.1 GenBank/EMBL/DDBJ: DAA06758.1 \| AY389302 \| AY389303 \| U00061
External Classifications	EC: 3.6.1.- [Hydrolases acting on acid anhydrides in phosphorous-containing anhydrides] EC: 3.6.4.-

Amino Acid Sequence (or in FASTA format)
1 MSKIVKRKEK KANDELTSLA EKIRAKALEN QKKLIEAEKE GGSESDSEED 51 ATAEKKKVLK SKSKSTVSTQ NENTNEDESF ESFSELNLVP ELIQACKNLN 101 YSKPTPIQSK AIPPALEGHD IIGLAQTGSG KTAAFAIPIL NRLWHDQEPY 151 YACILAPTRE LAQQIKETFD SLGSLMGVRS TCIVGGMNMM DQARDLMRKP 201 HIIIATPGRL MDHLENTKGF SLRKLKFLVM DEADRLLDME FGPVLDRILK 251 IIPTQERTTY LFSATMTSKI DKLQRASLTN PVKCAVSNKY QTVDTLVQTL 301 MVVPGGLKNT YLIYLLNEFI GKTMIIFTRT KANAERLSGL CNLLEFSATA 351 LHGDLNQNQR MGSLDLFKAG KRSILVATDV AARGLDIPSV DIVVNYDIPV 401 DSKSYIHRVG RTARAGRSGK SISLVSQYDL ELILRIEEVL GKKLPKESVD 451 KNIILTLRDS VDKANGEVVM EMNRRNKEKI ARGKGRRGRM MTRENMDMGE 501 R*

Amino Acid Sequence (or in FASTA format)

       1  MSKIVKRKEK KANDELTSLA EKIRAKALEN QKKLIEAEKE GGSESDSEED
      51  ATAEKKKVLK SKSKSTVSTQ NENTNEDESF ESFSELNLVP ELIQACKNLN
     101  YSKPTPIQSK AIPPALEGHD IIGLAQTGSG KTAAFAIPIL NRLWHDQEPY
     151  YACILAPTRE LAQQIKETFD SLGSLMGVRS TCIVGGMNMM DQARDLMRKP
     201  HIIIATPGRL MDHLENTKGF SLRKLKFLVM DEADRLLDME FGPVLDRILK
     251  IIPTQERTTY LFSATMTSKI DKLQRASLTN PVKCAVSNKY QTVDTLVQTL
     301  MVVPGGLKNT YLIYLLNEFI GKTMIIFTRT KANAERLSGL CNLLEFSATA
     351  LHGDLNQNQR MGSLDLFKAG KRSILVATDV AARGLDIPSV DIVVNYDIPV
     401  DSKSYIHRVG RTARAGRSGK SISLVSQYDL ELILRIEEVL GKKLPKESVD
     451  KNIILTLRDS VDKANGEVVM EMNRRNKEKI ARGKGRRGRM MTRENMDMGE
     501  R*

external links for Rrp3p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YPL+
Candida (CGD)	BioPIXIE	MIPS	YeastGFP
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains
YGOB	Complexome	YeastRC Structure Prediction (Seattle)
YOGY	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Rrp3p

1)	O'Day CL, et al. (1996) 18S rRNA processing requires the RNA helicase-like protein Rrp3. Nucleic Acids Res 24(16):3201-7