RSC30/YHR056C Protein Information Help

Standard Name Rsc30p
Systematic Name Yhr056cp
ORF Classification Verified
Description Component of the RSC chromatin remodeling complex; non-essential gene required for regulation of ribosomal protein genes and the cell wall/stress response; null mutants are osmosensitive; RSC30 has a paralog, RSC3, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description Remodel the Structure of Chromatin 5
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 883
Molecular Weight (Da) 101,334
Isoelectric Point (pI) 8.15

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Rsc30p (InterPro)
Physical Interactions There are 49 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000013B2A8 | P38781
MIPS: YHR056C
NCBI: 1176294 | 41593011 | 41629685 | NP_011923.2
GenBank/EMBL/DDBJ: DAA06749.1 | U00061
Amino Acid Sequence (or in FASTA format)
 
       1  MMDMQVRKVR KPPACTQCRK RKIGCDRAKP ICGNCVKYNK PDCFYPDGPG
      51  KMVAVPSASG MSTHGNGQGS NHFSQGNGVN QKNVMIQTQY PIMQTSIEAF
     101  NFSFNPSVDT AMQWTKAASY QNNNTNNNTA PRQNSSTVSS NVHGNTIVRS
     151  DSPDVPSMDQ IREYNTRLQL VNAQSFDYTD NPYSFNVGIN QDSAVFDLMT
     201  SPFTQEEVLI KEIDFLKNKL LDLQSLQLKS LKEKSNLNAD NTTANKINKT
     251  GENSKKGKVD GKRAGFDHQT SRTSQSSQKY FTALTITDVQ SLVQVKPLKD
     301  TPNYLFTKNF IIFRDHYLFK FYNILHDICH INQFKVSPPN NKNHQQYMEV
     351  CKVNFPPKAI IIETLNSESL NNLNIEEFLP IFDKTLLLEF VHNSFPNGDT
     401  CPSFSTVDLP LSQLTKLGEL TVLLLLLNDS MTLFNKQAIN NHVSALMNNL
     451  RLIRSQITLI NLEYYDQETI KFIAITKFYE SLYMHDDHKS SLDEDLSCLL
     501  SFQIKDFKLF HFLKKMYYSR HSLLGQSSFM VPAAENLSPI PASIDTNDIP
     551  LIANDLKLLE TQAKLINILQ GVPFYLPVNL TKIESLLETL TMGVSNTVDL
     601  YFHDNEVRKE WKDTLNFINT IVYTNFFLFV QNESSLSMAV QHSSNNNKTS
     651  NSERCAKDLM KIISNMHIFY SITFNFIFPI KSIKSFSSGN NRFHSNGKEF
     701  LFANHFIEIL QNFIAITFAI FQRCEVILYD EFYKNLSNEE INVQLLLIHD
     751  KILEILKKIE IIVSFLRDEM NSNGSFKSIK GFNKVLNLIK YMLRFSKKKQ
     801  NFARNSDNNN VTDYSQSAKN KNVLLKFPVS ELNRIYLKFK EISDFLMERE
     851  VVQRSIIIDK DLESDNLGIT TANFNDFYDA FYN*

external links for Rsc30p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
YGOB BioPIXIE MIPS
YOGY CYC2008 (complexes) Pfam domains

Complexome YeastRC Structure Prediction (Seattle)

DIP


GeneMANIA


YeastRC Two-Hybrid (Seattle)

References cited on this page View Complete Literature Guide for Rsc30p
1) Angus-Hill ML, et al.  (2001) A Rsc3/Rsc30 zinc cluster dimer reveals novel roles for the chromatin remodeler RSC in gene expression and cell cycle control. Mol Cell 7(4):741-51
2) Lorch Y, et al.  (1998) Activated RSC-nucleosome complex and persistently altered form of the nucleosome. Cell 94(1):29-34
3) Neely KE and Workman JL  (2002) The complexity of chromatin remodeling and its links to cancer. Biochim Biophys Acta 1603(1):19-29
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
5) Cairns BR, et al.  (1996) RSC, an essential, abundant chromatin-remodeling complex. Cell 87(7):1249-60