MSC7/YHR039C Protein Information Help

Standard Name Msc7p 1
Systematic Name Yhr039cp
ORF Classification Verified
Description Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc7 mutants are defective in directing meiotic recombination events to homologous chromatids (1, 2)
Name Description Meiotic Sister-Chromatid recombination 1
Experimental Data
Molecules/cell 2500 3
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 644
Molecular Weight (Da) 71,320
Isoelectric Point (pI) 7.61

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Msc7p (InterPro)
Transmembrane Domains There are 1 total predicted transmembrane domains (TMHMM)
Physical Interactions There are 27 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI000013B28E | P38694
MIPS: YHR039C
NCBI: 488180 | 6321828 | 731651 | NP_011904.1
GenBank/EMBL/DDBJ: DAA06730.1 | U00062
External Classifications EC: 1.2.1.- [Oxidoreductases, Acting on the aldehyde or oxo group of donors, With NAD(+) or NADP(+) as acceptor]
Amino Acid Sequence (or in FASTA format)
 
       1  MSKVYLNSDM INHLNSTVQA YFNLWLEKQN AIMRSQPQII QDNQKLIGIT
      51  TLVASIFTLY VLVKIISTPA KCSSSYKPVK FSLPAPEAAQ NNWKGKRSVS
     101  TNIWNPEEPN FIQCHCPATG QYLGSFPSKT EADIDEMVSK AGKAQSTWGN
     151  SDFSRRLRVL ASLHDYILNN QDLIARVACR DSGKTMLDAS MGEILVTLEK
     201  IQWTIKHGQR ALQPSRRPGP TNFFMKWYKG AEIRYEPLGV ISSIVSWNYP
     251  FHNLLGPIIA ALFTGNAIVV KCSEQVVWSS EFFVELIRKC LEACDEDPDL
     301  VQLCYCLPPT ENDDSANYFT SHPGFKHITF IGSQPVAHYI LKCAAKSLTP
     351  VVVELGGKDA FIVLDSAKNL DALSSIIMRG TFQSSGQNCI GIERVIVSKE
     401  NYDDLVKILN DRMTANPLRQ GSDIDHLENV DMGAMISDNR FDELEALVKD
     451  AVAKGARLLQ GGSRFKHPKY PQGHYFQPTL LVDVTPEMKI AQNEVFGPIL
     501  VMMKAKNTDH CVQLANSAPF GLGGSVFGAD IKECNYVANS LQTGNVAIND
     551  FATFYVCQLP FGGINGSGYG KFGGEEGLLG LCNAKSVCFD TLPFVSTQIP
     601  KPLDYPIRNN AKAWNFVKSF IVGAYTNSTW QRIKSLFSLA KEAS*

external links for Msc7p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Aspergillus (AspGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CGD) CYC2008 (complexes) Pfam domains
Candida (CandidaDB) Complexome YeastRC Structure Prediction (Seattle)
YGOB DIP

YOGY GeneMANIA

References cited on this page View Complete Literature Guide for Msc7p
1) Thompson DA and Stahl FW  (1999) Genetic control of recombination partner preference in yeast meiosis. Isolation and characterization of mutants elevated for meiotic unequal sister-chromatid recombination. Genetics 153(2):621-41
2) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
3) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41