GUT1/YHL032C Protein Information Help

Standard Name Gut1p 1
Systematic Name Yhl032cp
ORF Classification Verified
Description Glycerol kinase, converts glycerol to glycerol-3-phosphate; glucose repression of expression is mediated by Adr1p and Ino2p-Ino4p; derepression of expression on non-fermentable carbon sources is mediated by Opi1p and Rsf1p (2, 3)
Name Description Glycerol UTilization 2
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 709
Molecular Weight (Da) 79,824
Isoelectric Point (pI) 8.01

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Gut1p (InterPro)
Physical Interactions There are 8 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI00000530CB | P32190
MIPS: YHL032C
NCBI: 2289861 | 312423 | 417068 | 6321755 | NP_011831.1
GenBank/EMBL/DDBJ: DAA06653.1 | U11583 | X69049
External Classifications EC: 2.7.1.30 [Glycerol kinase]
Amino Acid Sequence (or in FASTA format)
 
       1  MFPSLFRLVV FSKRYIFRSS QRLYTSLKQE QSRMSKIMED LRSDYVPLIA
      51  SIDVGTTSSR CILFNRWGQD VSKHQIEYST SASKGKIGVS GLRRPSTAPA
     101  RETPNAGDIK TSGKPIFSAE GYAIQETKFL KIEELDLDFH NEPTLKFPKP
     151  GWVECHPQKL LVNVVQCLAS SLLSLQTINS ERVANGLPPY KVICMGIANM
     201  RETTILWSRR TGKPIVNYGI VWNDTRTIKI VRDKWQNTSV DRQLQLRQKT
     251  GLPLLSTYFS CSKLRWFLDN EPLCTKAYEE NDLMFGTVDT WLIYQLTKQK
     301  AFVSDVTNAS RTGFMNLSTL KYDNELLEFW GIDKNLIHMP EIVSSSQYYG
     351  DFGIPDWIME KLHDSPKTVL RDLVKRNLPI QGCLGDQSAS MVGQLAYKPG
     401  AAKCTYGTGC FLLYNTGTKK LISQHGALTT LAFWFPHLQE YGGQKPELSK
     451  PHFALEGSVA VAGAVVQWLR DNLRLIDKSE DVGPIASTVP DSGGVVFVPA
     501  FSGLFAPYWD PDARATIMGM SQFTTASHIA RAAVEGVCFQ ARAILKAMSS
     551  DAFGEGSKDR DFLEEISDVT YEKSPLSVLA VDGGMSRSNE VMQIQADILG
     601  PCVKVRRSPT AECTALGAAI AANMAFKDVN ERPLWKDLHD VKKWVFYNGM
     651  EKNEQISPEA HPNLKIFRSE SDDAERRKHW KYWEVAVERS KGWLKDIEGE
     701  HEQVLENFQ*

external links for Gut1p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily Organelle DB
Ashbya (AGD) BOND GPMdb (Mass Spec.) YPL+
Aspergillus (AspGD) BioPIXIE MIPS YeastGFP
Candida (CGD) CYC2008 (complexes) Pfam domains YeastRC Public Image Repository
Candida (CandidaDB) Complexome YeastRC Structure Prediction (Seattle)
YGOB DIP

YOGY GeneMANIA

References cited on this page View Complete Literature Guide for Gut1p
1) Ronnow, B. and Kielland-Brandt, M.C.  (1992) Personal Communication, Mortimer Map Edition 11
2) Pavlik P, et al.  (1993) The glycerol kinase (GUT1) gene of Saccharomyces cerevisiae: cloning and characterization. Curr Genet 24(1-2):21-5
3) Grauslund M, et al.  (1999) Expression of GUT1, which encodes glycerol kinase in Saccharomyces cerevisiae, is controlled by the positive regulators Adr1p, Ino2p and Ino4p and the negative regulator Opi1p in a carbon source-dependent fashion. Nucleic Acids Res 27(22):4391-8