YHL012W Protein Information

Systematic Name	Yhl012wp
ORF Classification	Uncharacterized
Description	Putative UTP glucose-1-phosphate uridylyltransferase; YHL012W has a paralog, UGP1, that arose from the whole genome duplication (1, 2)

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	493
Molecular Weight (Da)	56,000
Isoelectric Point (pI)	5.08

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Yhl012wp (InterPro)
Physical Interactions	There are 4 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000137AC2 \| P38709 MIPS: YHL012W NCBI: 2289882 \| 6321775 \| 731051 \| NP_011851.1 GenBank/EMBL/DDBJ: DAA06674.1 \| U11582
External Classifications	EC: 2.7.7.9 [UTP--glucose-1-phosphate uridylyltransferase]

Amino Acid Sequence (or in FASTA format)
1 MTVFSGVNKI EFEGTFEGIG KDVVMSQMIR ALQKHFPSIR DKNYEFSLFL 51 HIFQRYVLEN TSITHDLVCD KIRLPIIDEV VELDDIKNYG LLEGKLLSKL 101 AILKLTGKAN PIIGKESPLF EVKNGMSSLD VIVRQTQNLN VRYNSDVPLI 151 FMTSLETESQ VSNFLEEHYS SSKVRWKTVV QSSFPQIDKD RLLPIDLQIN 201 SHENDFWYPC GTGNLTDTLY FSGELDKLIA QGKEILFVSN VDNLGATGDL 251 NILNFIINEK IEYLVEVVER TANVSNTGVL ATYKGKLRSV YYNCLSNESA 301 STCRIVNTNN IWIDLKKLKV LIESNSLNLP IHSSESKITH KNEEIECLQF 351 KTQLVDCIAF FPNSRVLKVS RDRFLPLRTC KDLFLLKSTL YDLDSNGTFN 401 LYPLKFGLLP SIDLGDEFAT YETFKIGVPD IPNILELEHL TVMGNVFFGR 451 NITLKGTVII ICDENDVITV PDGSILENVT IWHKSQLEDM NGY*

Amino Acid Sequence (or in FASTA format)

       1  MTVFSGVNKI EFEGTFEGIG KDVVMSQMIR ALQKHFPSIR DKNYEFSLFL
      51  HIFQRYVLEN TSITHDLVCD KIRLPIIDEV VELDDIKNYG LLEGKLLSKL
     101  AILKLTGKAN PIIGKESPLF EVKNGMSSLD VIVRQTQNLN VRYNSDVPLI
     151  FMTSLETESQ VSNFLEEHYS SSKVRWKTVV QSSFPQIDKD RLLPIDLQIN
     201  SHENDFWYPC GTGNLTDTLY FSGELDKLIA QGKEILFVSN VDNLGATGDL
     251  NILNFIINEK IEYLVEVVER TANVSNTGVL ATYKGKLRSV YYNCLSNESA
     301  STCRIVNTNN IWIDLKKLKV LIESNSLNLP IHSSESKITH KNEEIECLQF
     351  KTQLVDCIAF FPNSRVLKVS RDRFLPLRTC KDLFLLKSTL YDLDSNGTFN
     401  LYPLKFGLLP SIDLGDEFAT YETFKIGVPD IPNILELEHL TVMGNVFFGR
     451  NITLKGTVII ICDENDVITV PDGSILENVT IWHKSQLEDM NGY*

external links for Yhl012wp

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
YGOB	BioPIXIE	MIPS
YOGY	CYC2008 (complexes)	Pfam domains
	Complexome	YeastRC Structure Prediction (Seattle)
	GeneMANIA

References cited on this page View Complete Literature Guide for Yhl012wp

1)	Hashimoto H, et al. (1997) Saccharomyces cerevisiae VIG9 encodes GDP-mannose pyrophosphorylase, which is essential for protein glycosylation. J Biol Chem 272(26):16308-14
2)	Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61