AIM9/YER080W Protein Information

Standard Name	Aim9p 1, 2
Systematic Name	Yer080wp
Alias	Fmp29p 3
ORF Classification	Verified
Description	Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays elevated frequency of mitochondrial genome loss (2, 4)
Name Description	Altered Inheritance rate of Mitochondria 2

Experimental Data
Molecules/cell	8200 5

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	627
Molecular Weight (Da)	72,414
Isoelectric Point (pI)	9.15

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Aim9p (InterPro)
Physical Interactions	There are 1 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000013ACAE \| P40053 MIPS: YER080W NCBI: 603318 \| 6320924 \| 731483 \| NP_011003.1 GenBank/EMBL/DDBJ: DAA07741.1 \| U18839

Amino Acid Sequence (or in FASTA format)
1 MIRYTVAGHS RRCVVGASKR VGAIKCITVA ATKRFISNKP NEVFTKLTND 51 NDPKRDAFFK YTWGSWLKND KQEKEKRFTK FSIEGLNRIL NDIYIQSNEM 101 AKAPDGKILP PVFNKNLTVS LVNNVVPKNI GKINPNEKVQ VTTLSSIHEG 151 KHHRIYKVDT NLNKAFILRI PYPLENENTL SYRIRSEVAT MDFADLKLGI 201 KVPKIFCYGV NSLNPVRQPF VLQEFIEGEL LMKDWDPLIE DGSSNQKKYD 251 NVIKQVSDFQ SKLVSLKLNA FGSIYFNNDL KDGNEKEFVK EDIYDGETNP 301 DLQNRWKIGP SVERCLWRHK SHLDFHKQMK PFLGPWPKKS PMDIIKNTGL 351 LEAENAKTRI AMKEAGSSAE LMYPRTLKEQ ITTYENLAKI APDLFNVKTK 401 AIPNMQELLS PRLFHPDLDP MNIIVNKEAQ EAYLLDFEGA CTKPFILQNS 451 PQFIAYDGPK IYDLKEDITD FDKLSEAEKV QYQFMYKRTR NQHQWEKKLN 501 DNNPKLITAV APPVKLLRSP YIAAVERKTE EEYLLIDESL LQLKEVWDIF 551 AQNELVNQKK FPLNYSKEDI ERHVEDLQKL HEKLISTPFA ATQGWIPQDM 601 FDQLLNSGSI VKQENGDYTV KQPEATK*

Amino Acid Sequence (or in FASTA format)

       1  MIRYTVAGHS RRCVVGASKR VGAIKCITVA ATKRFISNKP NEVFTKLTND
      51  NDPKRDAFFK YTWGSWLKND KQEKEKRFTK FSIEGLNRIL NDIYIQSNEM
     101  AKAPDGKILP PVFNKNLTVS LVNNVVPKNI GKINPNEKVQ VTTLSSIHEG
     151  KHHRIYKVDT NLNKAFILRI PYPLENENTL SYRIRSEVAT MDFADLKLGI
     201  KVPKIFCYGV NSLNPVRQPF VLQEFIEGEL LMKDWDPLIE DGSSNQKKYD
     251  NVIKQVSDFQ SKLVSLKLNA FGSIYFNNDL KDGNEKEFVK EDIYDGETNP
     301  DLQNRWKIGP SVERCLWRHK SHLDFHKQMK PFLGPWPKKS PMDIIKNTGL
     351  LEAENAKTRI AMKEAGSSAE LMYPRTLKEQ ITTYENLAKI APDLFNVKTK
     401  AIPNMQELLS PRLFHPDLDP MNIIVNKEAQ EAYLLDFEGA CTKPFILQNS
     451  PQFIAYDGPK IYDLKEDITD FDKLSEAEKV QYQFMYKRTR NQHQWEKKLN
     501  DNNPKLITAV APPVKLLRSP YIAAVERKTE EEYLLIDESL LQLKEVWDIF
     551  AQNELVNQKK FPLNYSKEDI ERHVEDLQKL HEKLISTPFA ATQGWIPQDM
     601  FDQLLNSGSI VKQENGDYTV KQPEATK*

external links for Aim9p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Aspergillus (AspGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CGD)	CYC2008 (complexes)	Pfam domains
Candida (CandidaDB)	Complexome
YGOB	GeneMANIA
YOGY

References cited on this page View Complete Literature Guide for Aim9p

1)	Gustavsson M and Ronne H (2008) Evidence that tRNA modifying enzymes are important in vivo targets for 5-fluorouracil in yeast. RNA 14(4):666-74
2)	Hess DC, et al. (2009) Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet 5(3):e1000407
3)	Meisinger, C., et al. (2004) personal communication
4)	Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54
5)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41